Genetic silencing of AKT induces melanoma cell death via mTOR suppression

GL Parkman, T Turapov, DA Kircher, WJ Burnett… - Molecular Cancer …, 2024 - AACR
Aberrant activation of the PI3K–AKT pathway is common in many cancers, including
melanoma, and AKT1, 2 and 3 (AKT1–3) are bona fide oncoprotein kinases with well …