An Integrated Computational Approaches for Designing of Potential Piperidine based Inhibitors of Alzheimer Disease by Targeting Cholinesterase and Monoamine …

M Sarfraz, MK Ibrahim, SA Ejaz, HM Attaullah… - Applied Biochemistry …, 2024 - Springer
The study aimed to evaluate the potential of piperidine-based 2H chromen-2-one derivatives
against targeted enzymes, ie, cholinesterase's and monoamine oxidase enzymes. The …

Microwave assisted synthesis, acetylcholinesterase inhibition and molecular docking studies of furo[2,3‐d]pyrido[1,2‐a]pyrimidin‐4‐one derivatives

S Yalduz, S Sarı, M Yılmaz - Journal of Heterocyclic Chemistry, 2024 - Wiley Online Library
A series of phenyl, substituted phenyl and thiophene bearing dihydrofuropyrimidin‐4‐ones
(3a‐p) were synthesized by Mn (OAc) 3 mediated, microwave irradiated radical cyclizations …