The Role of Glutathione in Age-Related Macular Degeneration (AMD)

S Brodzka, J Baszyński, K Rektor… - International Journal of …, 2024 - mdpi.com
Age-related macular degeneration (AMD) is a chronic disease that usually develops in older
people. Pathogenetic changes in this disease include anatomical and functional complexes …

[HTML][HTML] Pathogenesis of premature coronary artery disease: Focus on risk factors and genetic variants

H Wang, Z Liu, J Shao, M Jiang, X Lu, L Lin, L Wang… - Genes & …, 2022 - Elsevier
The development of premature coronary artery disease (PCAD) is dependent on both
genetic predisposition and traditional risk factors. Strategies for unraveling the genetic basis …

Long-term benefits and harms associated with genetic cholesteryl ester transfer protein deficiency in the general population

LT Nordestgaard, M Christoffersen… - JAMA …, 2022 - jamanetwork.com
Importance The balance between the potential long-term clinical benefits and harms
associated with genetic cholesteryl ester transfer protein (CETP) deficiency, mimicking …

[HTML][HTML] Genetic Insights into Age-Related Macular Degeneration

Bhumika, NS Bora, PS Bora - Biomedicines, 2024 - mdpi.com
One of the major causes of vision impairment among elderly people in developed nations is
age-related macular degeneration (AMD). The distinctive features of AMD are the …

Haplotypes of HTRA1 rs1120638, TIMP3 rs9621532, VEGFA rs833068, CFI rs10033900, ERCC6 rs3793784, and KCTD10 rs56209061 Gene Polymorphisms in …

R Liutkeviciene, A Vilkeviciute, G Gedvilaite… - Disease …, 2019 - Wiley Online Library
Background. To determine the impact of HTRA1 rs1120638, TIMP3 rs9621532, VEGFA
rs833068, CFI rs10033900, ERCC6 rs3793784, and KCTD10 rs56209061 genotypes on the …

IL-9 and IL-10 Single‐Nucleotide Variants and Serum Levels in Age‐Related Macular Degeneration in the Caucasian Population

A Vilkeviciute, D Cebatoriene… - Mediators of …, 2021 - Wiley Online Library
Considering the immunological impairment in age‐related macular degeneration (AMD), we
aimed to determine the associations of IL-9 rs1859430, rs2069870, rs11741137, rs2069885 …

SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, LIPC rs10468017, rs493258 and LPL rs12678919 genotypes and haplotype evaluation in patients with age …

R Liutkeviciene, A Vilkeviciute, L Kriauciuniene… - Gene, 2019 - Elsevier
Objective Age-related macular degeneration (AMD) is the leading cause of blindness in
elderly individuals in the developed countries. The etiology of AMD is thought to be …

Association of Genes in the High‐Density Lipoprotein Metabolic Pathway with Polypoidal Choroidal Vasculopathy in Asian Population: A Systematic Review and Meta …

M Yuan, R Han, C Zhang, Y Chen - Journal of Ophthalmology, 2018 - Wiley Online Library
Purpose. To assess the association of genes in the high‐density lipoprotein metabolic
pathway (HDLMP) with polypoidal choroidal vasculopathy (PCV) and the genetic difference …

SIRT1: Genetic variants and serum levels in age-related macular degeneration

K Kaikaryte, G Gedvilaite, A Vilkeviciute… - Life, 2022 - mdpi.com
Background: The aim of this paper was to determine the frequency of SIRT1 rs3818292,
rs3758391, rs7895833 single nucleotide polymorphism genotypes and SIRT1 serum levels …

RAD51B (rs8017304 and rs2588809), TRIB1 (rs6987702, rs4351379, and rs4351376), COL8A1 (rs13095226), and COL10A1 (rs1064583) Gene Variants with …

A Vilkeviciute, L Kriauciuniene, R Chaleckis… - Disease …, 2019 - Wiley Online Library
Background. Age‐related macular degeneration (AMD) is a progressive neurodegenerative
disease of a central part of the neural retina (macula) and a leading cause of blindness in …