Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Recent developments of carbon dots in biosensing: A review

C Ji, Y Zhou, RM Leblanc, Z Peng - ACS sensors, 2020 - ACS Publications
Early diagnosis of diseases is of great importance because it increases the chance of a cure
and significantly reduces treatment costs. Thus, development of rapid, sensitive, and reliable …

Metal–organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay

X Liu, X Gao, L Yang, Y Zhao, F Li - Analytical chemistry, 2021 - ACS Publications
The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …

Materials with tunable optical properties for wearable epidermal sensing in health monitoring

F Han, T Wang, G Liu, H Liu, X Xie, Z Wei… - Advanced …, 2022 - Wiley Online Library
Advances in wearable epidermal sensors have revolutionized the way that physiological
signals are captured and measured for health monitoring. One major challenge is to convert …

Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Y Zhang, M Li, X Gao, Y Chen, T Liu - Journal of hematology & oncology, 2019 - Springer
In the fight against cancer, early detection is a key factor for successful treatment. However,
the detection of cancer in the early stage has been hindered by the intrinsic limits of …

Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping

X Su, X Liu, Y Xie, M Chen, C Zheng, H Zhong, M Li - ACS nano, 2023 - ACS Publications
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …

Nucleic acid aptamers for molecular diagnostics and therapeutics: advances and perspectives

L Li, S Xu, H Yan, X Li, HS Yazd, X Li… - Angewandte Chemie …, 2021 - Wiley Online Library
The advent of SELEX (systematic evolution of ligands by exponential enrichment)
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …

Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers

C Liu, J Zhao, F Tian, L Cai, W Zhang, Q Feng… - Nature biomedical …, 2019 - nature.com
Non-invasive assays for early cancer screening are hampered by challenges in the isolation
and profiling of circulating biomarkers. Here, we show that surface proteins from serum …

Electrochemical biosensors for the detection of lung cancer biomarkers: A review

A Khanmohammadi, A Aghaie, E Vahedi, A Qazvini… - Talanta, 2020 - Elsevier
Cancer is one of the most widespread challenges and important diseases, which has the
highest mortality rate. Lung cancer is the most common type of cancer, so that about 25% of …