In vitro and in vivo models for studying SARS-CoV-2, the etiological agent responsible for COVID-19 pandemic

RB Rosa, WM Dantas, JCF do Nascimento… - Viruses, 2021 - mdpi.com
The emergence and rapid worldwide spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has prompted the scientific community to rapidly develop in …

Neutralisation of SARS-CoV-2 lineage P. 1 by antibodies elicited through natural SARS-CoV-2 infection or vaccination with an inactivated SARS-CoV-2 vaccine: an …

WM Souza, MR Amorim, R Sesti-Costa… - The Lancet …, 2021 - thelancet.com
Background Mutations accrued by SARS-CoV-2 lineage P. 1—first detected in Brazil in early
January, 2021—include amino acid changes in the receptor-binding domain of the viral …

Viability of SARS-CoV-2 in river water and wastewater at different temperatures and solids content

LC De Oliveira, AF Torres-Franco, BC Lopes… - Water research, 2021 - Elsevier
COVID-19 patients can excrete viable SARS-CoV-2 virus via urine and faeces, which has
raised concerns over the possibility of COVID-19 transmission via aerosolized contaminated …

Ultrarapid on-site detection of SARS-CoV-2 infection using simple ATR-FTIR spectroscopy and an analysis algorithm: High sensitivity and specificity

VG Barauna, MN Singh, LL Barbosa… - Analytical …, 2021 - ACS Publications
There is an urgent need for ultrarapid testing regimens to detect the severe acute respiratory
syndrome coronavirus 2 [SARS-CoV-2] infections in real-time within seconds to stop its …

SARS-CoV-2 genomic surveillance in Brazil: a systematic review with scientometric analysis

D Menezes, PLC Fonseca, JLF de Araújo, RP Souza - Viruses, 2022 - mdpi.com
Several studies have monitored the SARS-CoV-2 variants in Brazil throughout the
pandemic. Here, we systematically reviewed and conducted a scientometric analysis of the …

Convalescent plasma for COVID-19 in hospitalised patients: an open-label, randomised clinical trial

L Sekine, B Arns, BR Fabro… - European …, 2022 - publications.ersnet.org
Background The effects of convalescent plasma (CP) therapy in hospitalised patients with
coronavirus disease 2019 (COVID-19) remain uncertain. This study investigates the effect of …

[HTML][HTML] UV-C (254 nm) lethal doses for SARS-CoV-2

CP Sabino, FP Sellera, DF Sales-Medina… - Photodiagnosis and …, 2020 - ncbi.nlm.nih.gov
The rapid and continuous spread of SARS-CoV-2, responsible for COVID-19, has been
challenging global health systems and many strategies have been proposed to face the …

Screening for SARS‐CoV‐2 antibodies in convalescent plasma in Brazil: Preliminary lessons from a voluntary convalescent donor program

S Wendel, JM Kutner, R Machado… - …, 2020 - Wiley Online Library
Abstract Background Coronavirus disease 2019 (COVID‐19) convalescent plasma (CCP)
collection began in two Brazilian hospitals for treatment of severe/critical patients. Methods …

Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease

V Srinivasan, H Brognaro, PR Prabhu… - Communications …, 2022 - nature.com
Abstract SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the
cysteine-protease activity, facilitating cleavage of the viral polypeptide chain, PLpro has the …

Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein

JT Castro, P Azevedo, MJ Fumagalli… - Nature …, 2022 - nature.com
Both T cells and B cells have been shown to be generated after infection with SARS-CoV-2
yet protocols or experimental models to study one or the other are less common. Here, we …