Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …

Summary Glucagon-like peptide-1 (GLP-1) is a signal peptide released from
enteroendocrine cells of the lower intestine. GLP-1 exerts anorectic and antimotility actions …

Breathing is an intrinsic natural behavior and physiological process that maintains life. The
rhythmic exchange of gases regulates the delicate balance of chemical constituents within …

Cytokines employ downstream Janus kinases (JAKs) to promote chronic inflammatory
diseases. JAK1-dependent type 2 cytokines drive allergic inflammation, and patients with …

Dense tumor innervation is associated with enhanced cancer progression and poor
prognosis. We observed innervation in breast, prostate, pancreatic, lung, liver, ovarian, and …

Electrical excitability—the ability to fire and propagate action potentials—is a signature
feature of neurons. How neurons become excitable during development and whether …

Background: It had been shown that selective cardiac vagal activation holds great potential
for heart regeneration. Optogenetics has clinical translation potential as a novel means of …

Objective. Sensory nerves of the peripheral nervous system (PNS) transmit afferent signals
from the body to the brain. These peripheral nerves are composed of distinct subsets of …

Pulmonary vagal nociceptors defend the airways. Cardiopulmonary vagal nociceptors
synapse in the nucleus tractus solitarius (NTS). Evidence has demonstrated the …

Resumen La Psico-Inmuno-Neuro-Endocrinología (PINE/PNIE) se edificó sobre los
hombros de grandes pioneros, donde la palabra integración se expande como concepto no …