Immune memory in aging: a wide perspective covering microbiota, brain, metabolism, and epigenetics

O Bulut, G Kilic, J Domínguez-Andrés - Clinical reviews in allergy & …, 2022 - Springer
Non-specific innate and antigen-specific adaptive immunological memories are vital
evolutionary adaptations that confer long-lasting protection against a wide range of …

Microbiota–host interactions shape ageing dynamics

M Popkes, DR Valenzano - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Occupying the interface between host and environment, host-associated microbes play
fundamental roles in nutrient absorption, essential metabolite synthesis, development of the …

Alterations in the oral microbiome in HIV infection: causes, effects and potential interventions

S Li, B Su, QS He, H Wu, T Zhang - Chinese medical journal, 2021 - mednexus.org
A massive depletion of CD4+ T lymphocytes has been described in early and acute human
immunodeficiency virus (HIV) infection, leading to an imbalance between the human …

Targeting Th17 cells in HIV-1 remission/cure interventions

A Fert, LR Marchand, TRW Salinas, P Ancuta - Trends in Immunology, 2022 - cell.com
Since the discovery of HIV-1, progress has been made in deciphering the viral replication
cycle and mechanisms of host–pathogen interactions that has facilitated the implementation …

Sustained gut dysbiosis and intestinal inflammation show correlation with weight gain in person with chronic HIV infection on antiretroviral therapy

A Ishizaka, M Koga, T Mizutani, Y Suzuki, T Matano… - BMC microbiology, 2024 - Springer
Background Person with human immunodeficiency virus type-1 (PWH) are prone to chronic
inflammation due to residual viral production, even with antiretroviral therapy (ART), which …

[HTML][HTML] Growth faltering regardless of chronic diarrhea is associated with mucosal immune dysfunction and microbial dysbiosis in the gut lumen

NS Rhoades, SM Hendrickson, K Prongay, A Haertel… - Mucosal …, 2021 - Elsevier
Despite the impact of childhood diarrhea on morbidity and mortality, our understanding of its
sequelae has been significantly hampered by the lack of studies that examine samples …

Cardiac and renal comorbidities in aging people living with HIV

K McCutcheon, U Nqebelele, L Murray… - Circulation …, 2024 - Am Heart Assoc
Contemporary World Health Organization data indicates that≈ 39 million people are living
with the human immunodeficiency virus. Of these, 24 million have been reported to have …

Resilience integrates concepts in aging research

D Promislow, RM Anderson, M Scheffer, B Crespi… - Iscience, 2022 - cell.com
Aging research is unparalleled in the breadth of disciplines it encompasses, from
evolutionary studies examining the forces that shape aging to molecular studies uncovering …

γδ T‐cell responses during HIV infection and antiretroviral therapy

JA Juno, EM Eriksson - Clinical & translational immunology, 2019 - Wiley Online Library
HIV infection is associated with a rapid and sustained inversion of the Vδ1: Vδ2 T‐cell ratio
in peripheral blood. Studies of antiretroviral therapy (ART)‐treated cohorts suggest that ART …

HIV, sexual orientation, and gut microbiome interactions

S Tuddenham, WL Koay, C Sears - Digestive diseases and sciences, 2020 - Springer
Recent studies have raised interest in the possibility that dysbiosis of the gut microbiome (ie,
the communities of bacteria residing in the intestine) in HIV-infected patients could …