A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications

A Ahmady, NHA Samah - International Journal of Pharmaceutics, 2021 - Elsevier
Bioadhesive polymers offer versatility to medical and pharmaceutical inventions. The
incorporation of such materials to conventional dosage forms or medical devices may confer …

Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles

JO Morales, DJ Brayden - Current opinion in pharmacology, 2017 - Elsevier
Highlights•The buccal route has been exploited for selected potent small
molecules.•Research to achieve buccal insulin delivery is based on avoiding the …

Ionic liquid-mediated delivery of insulin to buccal mucosa

A Vaidya, S Mitragotri - Journal of Controlled Release, 2020 - Elsevier
Buccal drug delivery offers a potential non-invasive means of delivering therapeutics to
patients. Despite the promise, the feasibility of transporting proteins and peptides into …

Mucoadhesive formulations: Innovations, merits, drawbacks, and future outlook

A Kumar, PK Naik, D Pradhan, G Ghosh… - Pharmaceutical …, 2020 - Taylor & Francis
Mucosa has now been recognized as a potential site for both local and systemic delivery of
therapeutics. Mucoadhesive drug delivery systems with customizable release profiles have …

S-protected gellan gum: Decisive approach towards mucoadhesive antimicrobial vaginal films

A Jalil, MH Asim, NMN Le, F Laffleur… - International journal of …, 2019 - Elsevier
The aim of this study was to synthesize novel polymeric excipients forming mucoadhesive
films for treatment of vaginal microbial infections. 2-(2-Amino ethyldisulfanyl) nicotinic acid …

Thiolated polymers: An overview of mucoadhesive properties and their potential in drug delivery via mucosal tissues

K Mfoafo, R Mittal, A Eshraghi, Y Omidi… - Journal of Drug Delivery …, 2023 - Elsevier
Thiolated polymers, or thiomers, are a class of polymers that exhibit unique mucoadhesive
properties, allowing them to form strong covalent bonds with cysteine-rich subdomains of …

Thiolated cellulose: A dual-acting mucoadhesive and permeation-enhancing polymer

G Kali, B Özkahraman, F Laffleur, P Knoll… - …, 2023 - ACS Publications
This study aims to design an anionic, thiolated cellulose derivative and to evaluate its
mucoadhesive and permeation-enhancing properties utilizing enoxaparin as a model drug …

Emerging strategies for enhancing buccal and sublingual administration of nutraceuticals and pharamaceuticals

Y Guo, AP Singh - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
As a relatively convenient route of administration, oral route of drug delivery can be used for
topical and systemic administration. However, conventional oral administration through …

Thiolated hydroxypropyl-β-cyclodextrin as mucoadhesive excipient for oral delivery of budesonide in liquid paediatric formulation

V Laquintana, MH Asim, A Lopedota… - International journal of …, 2019 - Elsevier
Budesonide (BUD) is a low water soluble (S 0= 5.028· 10− 5 M) corticosteroid used as
preferred therapy for the treatment of Eosinophilic Esophagitis (EoE), a chronic allergic …

Development of pre-activated α-cyclodextrin as a mucoadhesive excipient for intra-vesical drug delivery

M Ijaz, M Prantl, N Lupo, F Laffleur, MH Asim… - International Journal of …, 2017 - Elsevier
The study was designed to synthesize and characterize pre-activated α-cyclodextrin (α-CD)
derivatives as mucus adhering excipients for intra-vesical drug delivery. Sodium periodate …