Mitochondrial ROS control of cancer

MPS Idelchik, U Begley, TJ Begley… - Seminars in cancer …, 2017 - Elsevier
Mitochondria serves a primary role in energy maintenance but also function to govern levels
of mitochondria-derived reactive oxygen species (mROS). ROS have long been established …

Prostate cancer management: long-term beliefs, epidemic developments in the early twenty-first century and 3PM dimensional solutions

R Kucera, L Pecen, O Topolcan, AR Dahal… - EPMA Journal, 2020 - Springer
In the early twenty-first century, societies around the world are facing the paradoxal
epidemic development of PCa as a non-communicable disease. PCa is the most frequently …

[HTML][HTML] Potassium homeostasis, oxidative stress, and human disease

UK Udensi, PB Tchounwou - International journal of clinical and …, 2017 - ncbi.nlm.nih.gov
Potassium is the most abundant cation in the intracellular fluid and it plays a vital role in the
maintenance of normal cell functions. Thus, potassium homeostasis across the cell …

Quercetin inhibits prostate cancer by attenuating cell survival and inhibiting anti-apoptotic pathways

AB Ward, H Mir, N Kapur, DN Gales… - World journal of surgical …, 2018 - Springer
Background Despite recent advances in diagnosis and treatment, prostate cancer (PCa)
remains the leading cause of cancer-related deaths in men. Current treatments offered in the …

Recent development of copper (II) complexes of polypyridyl ligands in chemotherapy and photodynamic therapy

J Rani J, S Roy - ChemMedChem, 2023 - Wiley Online Library
Cancer is a deadly disease associated with abnormal cell growth and invasion to various
parts of the body. Many drugs such as cisplatin and carboplatin have been used for the …

Serum deprivation initiates adaptation and survival to oxidative stress in prostate cancer cells

ESZ White, NM Pennant, JR Carter, O Hawsawi… - Scientific reports, 2020 - nature.com
Inadequate nutrient intake leads to oxidative stress disrupting homeostasis, activating
signaling, and altering metabolism. Oxidative stress serves as a hallmark in developing …

Glutathione Peroxidase 3 induced mitochondria-mediated apoptosis via AMPK/ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway …

Y Li, Y Zhou, D Liu, Z Wang, J Qiu, J Zhang… - Journal of Translational …, 2023 - Springer
Background Benign prostatic hyperplasia (BPH) is a common disease in elderly men, mainly
resulted from an imbalance between cell proliferation and death. Glutathione peroxidase 3 …

Chemical characterization and in vivo antioxidant activity of parsley (Petroselinum crispum) aqueous extract

NM de Menezes Epifanio, LRI Cavalcanti… - Food & function, 2020 - pubs.rsc.org
Twenty-nine flavonoid glycosides were identified in the aqueous extract (PC) of
Petroselinum crispum var. crispum leaves and apiin, the major compound, was isolated …

Targeting crosstalk between Nrf-2, NF-κB and androgen receptor signaling in prostate cancer

N Khurana, SC Sikka - Cancers, 2018 - mdpi.com
Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in
the initiation, development and progression of prostate cancer (PCa). Numerous papers in …

Vitamin D deficiency: a potential risk factor for cancer in obesity?

S Migliaccio, A Di Nisio, S Magno, F Romano… - International Journal of …, 2022 - nature.com
Obesity is considered an abnormal or excessive accumulation of adipose tissue, due to a
prolonged positive energy balance that arises when energy intake is greater than energy …