Biofilms are of great importance in infection control and healthcare-associated infections
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …

Chronic leg ulcers affect 1–2% of the general population and are related to increased
morbidity and health costs. Staphylococcus aureus and Pseudomonas aeruginosa are the …

Emergent resistance to all clinical antibiotics calls for the next generation of therapeutics.
Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

Background is provided on biofilms, including their formation, tolerance mechanisms,
structure, and morphology within the context of chronic wounds. The features of biofilms in …

Background: Despite a growing consensus that biofilms contribute to a delay in the healing
of chronic wounds, conflicting evidence pertaining to their identification and management …

Wound dressings based on injectable thermo-sensitive hydrogel possess several
advantages over preformed conventional dressings such as rapid reversible sol-gel …

The emergence of multidrug resistance has become an alarming and lifethreatening
phenomenon for humans. Various mechanisms are involved in the development of …

Pseudomonas aeruginosa is a ubiquitous organism that is the focus of intense research
because of its prominent role in disease. Due to its relatively large genome and flexible …

Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the
innate barrier function of the skin and dermal appendages, facilitating the development of …