[HTML][HTML] Substrate curvature as a cue to guide spatiotemporal cell and tissue organization

SJP Callens, RJC Uyttendaele, LE Fratila-Apachitei… - Biomaterials, 2020 - Elsevier
Recent evidence clearly shows that cells respond to various physical cues in their
environments, guiding many cellular processes and tissue morphogenesis, pathology, and …

Physics of adherent cells

US Schwarz, SA Safran - Reviews of Modern Physics, 2013 - APS
One of the most unique physical features of cell adhesion to external surfaces is the active
generation of mechanical force at the cell-material interface. This includes pulling forces …

Surface curvature differentially regulates stem cell migration and differentiation via altered attachment morphology and nuclear deformation

M Werner, SBG Blanquer, SP Haimi, G Korus… - Advanced …, 2017 - Wiley Online Library
Signals from the microenvironment around a cell are known to influence cell behavior.
Material properties, such as biochemical composition and substrate stiffness, are today …

Curved nanofiber network induces cellular bridge formation to promote stem cell mechanotransduction

Q Sun, F Pei, M Zhang, B Zhang, Y Jin… - Advanced …, 2023 - Wiley Online Library
Remarkable exertions are directed to reveal and understand topographic cues that induce
cell mechanical sensitive responses including lineage determination. Extracellular matrix …

United we stand–integrating the actin cytoskeleton and cell–matrix adhesions in cellular mechanotransduction

US Schwarz, ML Gardel - Journal of cell science, 2012 - journals.biologists.com
Many essential cellular functions in health and disease are closely linked to the ability of
cells to respond to mechanical forces. In the context of cell adhesion to the extracellular …

Mechanics of the F-actin cytoskeleton

J Stricker, T Falzone, ML Gardel - Journal of biomechanics, 2010 - Elsevier
Dynamic regulation of the filamentous actin (F-actin) cytoskeleton is critical to numerous
physical cellular processes, including cell adhesion, migration and division. Each of these …

Geometry as a factor for tissue growth: towards shape optimization of tissue engineering scaffolds

CM Bidan, KP Kommareddy, M Rumpler… - Advanced …, 2013 - Wiley Online Library
Scaffolds for tissue engineering are usually designed to support cell viability with large
adhesion surfaces and high permeability to nutrients and oxygen. Recent experiments …

Two‐component polymer scaffolds for controlled three‐dimensional cell culture

F Klein, B Richter, T Striebel, CM Franz… - Advanced …, 2011 - infona.pl
Two‐component 3D polymer scaffolds with distinct mechanical and protein‐binding
properties are fabricated using direct laser writing. With this method, full control over the …

Stress fibres are embedded in a contractile cortical network

T Vignaud, C Copos, C Leterrier, M Toro-Nahuelpan… - Nature materials, 2021 - nature.com
Contractile actomyosin networks are responsible for the production of intracellular forces.
There is increasing evidence that bundles of actin filaments form interconnected and …

The shape of motile cells

A Mogilner, K Keren - Current Biology, 2009 - cell.com
Motile cells—fan-like keratocytes, hand-shaped nerve growth cones, polygonal fibroblasts,
to name but a few—come in different shapes and sizes. We discuss the origins of this …