HIV–Mycobacterium tuberculosis co-infection: a 'danger-couple model' of disease pathogenesis

EM Shankar, R Vignesh, R Ellegård… - Pathogens and …, 2014 - academic.oup.com
Tuberculosis (TB) and human immunodeficiency virus (HIV) infection interfere and impact
the pathogenesis phenomena of each other. Owing to atypical clinical presentations and …

Biomarkers of HIV immune reconstitution inflammatory syndrome

S Bonham, DB Meya, PR Bohjanen… - Biomarkers in …, 2008 - Taylor & Francis
Dysregulation of the immune system drives HIV pathogenesis. As we develop new ways to
treat HIV and AIDS, we encounter new clinical ramifications of our treatment on regulatory …

Natural Killer Cell Activation Distinguishes Mycobacterium tuberculosis–Mediated Immune Reconstitution Syndrome From Chronic HIV and HIV/MTB Coinfection

F Conradie, AS Foulkes, P Ive, X Yin… - JAIDS Journal of …, 2011 - journals.lww.com
Background With increased access to antiretroviral treatment (ART), immune reconstitution
inflammatory syndrome (IRIS) in Mycobacterium tuberculosis (MTB)–infected populations …

[HTML][HTML] Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination

M Manrique, PA Kozlowski, SW Wang, RL Wilson… - Mucosal …, 2009 - Elsevier
Preventive human immunodeficiency virus (HIV) vaccination may require induction of virus-
specific immune responses at mucosal sites to contain viral infection locally after exposure …

Tuberculosis-associated immune reconstitution inflammatory syndrome—an extempore game of misfiring with defense arsenals

R Vignesh, P Balakrishnan, HY Tan, YK Yong, V Velu… - Pathogens, 2023 - mdpi.com
The lethal combination involving TB and HIV, known as “syndemic” diseases, synergistically
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …

Intestinal barrier dysfunction mediates Whipple's disease immune reconstitution inflammatory syndrome (IRIS)

J Friebel, K Schinnerling… - Immunity …, 2022 - Wiley Online Library
Abstract Background & Aims Classical Whipple's disease (CWD) affects the gastrointestinal
tract and causes chronic diarrhea, malabsorption, and barrier dysfunction with microbial …

[HTML][HTML] Bacillus Calmette–Guérin (BCG) vaccine-induced complications in children treated with highly active antiretroviral therapy

JJ Nuttall, MA Davies, GD Hussey, BS Eley - International Journal of …, 2008 - Elsevier
OBJECTIVE: To describe the frequency, risk factors, and clinical features of bacillus
Calmette-Guérin (BCG) complications in HIV-infected children treated with highly active …

Multi-analyte profiling of ten cytokines in South African HIV-infected patients with Immune Reconstitution Inflammatory Syndrome (IRIS)

CM Worsley, MS Suchard, WS Stevens… - AIDS Research and …, 2010 - Springer
Background Immune reconstitution inflammatory syndrome (IRIS) is an important
complication of HAART in sub-Saharan Africa, where opportunistic infections (OIs) including …

Does CD4+ CD25+ foxp3+ cell (Treg) and IL-10 profile determine susceptibility to immune reconstitution inflammatory syndrome (IRIS) in HIV disease?

EM Shankar, R Vignesh, V Velu, KG Murugavel… - Journal of …, 2008 - Springer
HIV-specific T-lymphocyte responses that underlie IRIS are incomplete and largely remain
hypothetical. Of the several mechanisms presented by the host to control host …

Immunopathogenesis of immune reconstitution disease in HIV patients responding to antiretroviral therapy

L Kestens, N Seddiki, PR Bohjanen - Current Opinion in HIV and …, 2008 - journals.lww.com
Although the precise mechanism of immune reconstitution disease is not well understood, it
is probably related to rapid restoration of pathogen-specific immune responses and poor …