Marginal-zone lymphomas

D Rossi, F Bertoni, E Zucca - New England journal of medicine, 2022 - Mass Medical Soc
Marginal-Zone Lymphomas The third most common lymphoma, MZL is usually indolent and
often a consequence of chronic antigenic stimulation from a pathogen such as Helicobacter …

[HTML][HTML] Recent advances in understanding the biology of marginal zone lymphoma

F Bertoni, D Rossi, E Zucca - F1000Research, 2018 - ncbi.nlm.nih.gov
There are three different marginal zone lymphomas (MZLs): the extranodal MZL of mucosa-
associated lymphoid tissue (MALT) type (MALT lymphoma), the splenic MZL, and the nodal …

Large B-cell lymphomas with CCND1 rearrangement have different immunoglobulin gene breakpoints and genomic profile than mantle cell lymphoma

E Özoğul, A Montaner, M Pol, G Frigola… - Blood Cancer …, 2024 - nature.com
Mantle cell lymphoma (MCL) is genetically characterized by the IG:: CCND1 translocation
mediated by an aberrant V (D) J rearrangement. CCND1 translocations and overexpression …

IgIDivA: immunoglobulin intraclonal diversification analysis

L Zaragoza-Infante, V Junet… - Briefings in …, 2022 - academic.oup.com
Intraclonal diversification (ID) within the immunoglobulin (IG) genes expressed by B cell
clones arises due to ongoing somatic hypermutation (SHM) in a context of continuous …

Molecular pathogenesis of splenic and nodal marginal zone lymphoma

V Spina, D Rossi - Best Practice & Research Clinical Haematology, 2017 - Elsevier
Genomic studies have improved our understanding of the biological basis of splenic (SMZL)
and nodal (NMZL) marginal zone lymphoma by providing a comprehensive and unbiased …

Disease‐biased and shared characteristics of the immunoglobulin gene repertoires in marginal zone B cell lymphoproliferations

A Xochelli, V Bikos, E Polychronidou… - The Journal of …, 2019 - Wiley Online Library
The B cell receptor immunoglobulin (Ig) gene repertoires of marginal zone (MZ)
lymphoproliferations were analyzed in order to obtain insight into their ontogenetic …

New insights into the biology and diagnosis of splenic marginal zone lymphomas

M Donzel, L Baseggio, J Fontaine, F Pesce… - Current …, 2021 - mdpi.com
Splenic marginal zone lymphoma (SMZL) is a small B-cell lymphoma, which has been
recognized as a distinct pathological entity since the WHO 2008 classification. It classically …

Improved biological insight and influence on management in indolent lymphoma. Talk 3: update on nodal and splenic marginal zone lymphoma

C Thieblemont - Hematology 2014, the American Society of …, 2017 - ashpublications.org
Splenic marginal zone lymphoma (SMZL) and nodal marginal zone lymphoma (NMZL) are
rare indolent chronic B-cell lymphomas. Prognosis is typically good with median survival …

Splenic marginal zone lymphomas in acquired C1-inhibitor deficiency: clinical and molecular characterization

M Sbattella, A Zanichelli, P Ghia, V Gattei, C Suffritti… - Medical Oncology, 2018 - Springer
Angioedema due to acquired deficiency of the inhibitor of the first component of complement
(C1-INH) is a rare disease known as acquired angioedema (AAE). About 70% of patients …

NF-κB deregulation in splenic marginal zone lymphoma

V Spina, D Rossi - Seminars in cancer biology, 2016 - Elsevier
Splenic marginal zone lymphoma is a rare mature B-cell malignancy involving the spleen,
bone marrow and blood. Over the past years, the rapid expansion of sequencing …