CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia

N Jena, J Sheng, JK Hu, W Li, W Zhou, G Lee… - Leukemia, 2016 - nature.com
T-cell acute lymphoblastic leukemia (T-ALL) is a high-risk subset of acute leukemia,
characterized by frequent activation of Notch1 or AKT signaling, where new therapeutic …

Key candidate genes and pathways in T lymphoblastic leukemia/lymphoma identified by bioinformatics and serological analyses

Y Ren, H Liang, Y Huang, Y Miao, R Li… - Frontiers in …, 2024 - frontiersin.org
T-cell acute lymphoblastic leukemia (T-ALL)/T-cell lymphoblastic lymphoma (T-LBL) is an
uncommon but highly aggressive hematological malignancy. It has high recurrence and …

Abnormally high expression of POLD1, MCM2, and PLK4 promotes relapse of acute lymphoblastic leukemia

S Li, C Wang, W Wang, W Liu, G Zhang - Medicine, 2018 - journals.lww.com
This study aimed to explore the underlying mechanism of relapsed acute lymphoblastic
leukemia (ALL). Datasets of GSE28460 and GSE18497 were downloaded from Gene …

NPM-ALK is a key regulator of the oncoprotein FOXM1 in ALK-positive anaplastic large cell lymphoma

M Haque, J Li, YH Huang, M Almowaled, CJ Barger… - Cancers, 2019 - mdpi.com
Forkhead Box M1 (FOXM1) is an oncogenic transcription factor implicated in the
pathogenesis of solid and hematologic cancers. In this study, we examined the significance …

Siomycin A induces reactive oxygen species‑mediated cytotoxicity in ovarian cancer cells

X Shao, F Zhang, X Gao, F Xu - Oncology Letters, 2021 - spandidos-publications.com
Ovarian cancer is one of the leading causes of cancer‑related death among women
worldwide and accounts for 4% of all cancer cases in female patients. To date, ovarian …

[PDF][PDF] Evaluation of Chromosomal Instability in Jurkat Cell Line through Serial Passages

Z He - 2022 - ourarchive.otago.ac.nz
Jurkat cell line is one of the most commonly used T lymphoblast cell models; however, their
stability during in vitro culture is of particular concern. Previous work has suggested that …

[DOC][DOC] NPM-ALK is a key regulator of the oncoprotein FOXM1 in ALK-positive anaplastic large cell lymphoma: identification of a novel role for NPM1 in the …

M Haque, J Li, YH Huang, M Almowaled, CJ Barger… - api.repository.cam.ac.uk
ABSTRACT Forkhead Box M1 (FOXM1) is an oncogenic transcription factor implicated in the
pathogenesis of solid and hematologic cancers. Here, we examined the significance of …

[PDF][PDF] Estudio de vías de receptores hormonales y los factores de transcripción forkhead box (FOX) en el cáncer de próstata

JN Brandani - 2020 - bibliotecadigital.exactas.uba.ar
El cáncer de próstata es el segundo tipo de cáncer más comúnmente diagnosticado en
Argentina (considerando ambos sexos) y es la cuarta causa de muerte por cáncer. Sin …

The role of transcription factor FOXM1 in multiple myeloma

KA Thornton - 2019 - search.proquest.com
Background: Multiple myeloma (MM) is an incurable malignancy of monoclonal plasma cells
that crowd the bone marrow and lead to disease features such as anemia, hypercalcemia …

[引用][C] Роль окислительной модификации белков и их деградации, тиолдисульфидной системы в механизмах дизрегуляции апоптоза при опухолевой …

ОЛ Носарева - 2016 - б. и.