Standard treatment of primary and metastatic brain tumours includes high-dose
megavoltage-range radiation to the cranial vault. About half of patients survive> 6 months …

Introduction High-grade gliomas cause cognitive impairment in those who suffer from them.
However, there is a lack of precise data describing the cognitive deficit that occurs in this …

Background and purpose Brain radiotherapy is limited in part by damage to white matter,
contributing to neurocognitive decline. We utilized diffusion tensor imaging (DTI) with …

Background EORTC study 22033–26033 showed no difference in progression-free survival
between high-risk low-grade glioma receiving either radiotherapy (RT) or temozolomide …

Life expectancy of patients treated for brain tumors has lengthened due to the therapeutic
improvements. Cognitive impairment has been described following brain radiotherapy, but …

Exposure to ionizing radiation, mechanical trauma, toxic chemicals or infections, or
combinations thereof (ie, combined injury) can induce organic injury to brain tissues, the …

Background and purpose To compare the structural and hemodynamic changes of healthy
brain tissue in the cerebral hemisphere contralateral to the tumor following photon and …

Simple Summary Radiotherapy is one of the most important treatment options against
cancer. Irradiation of cancerous tissue either directly destroys the cancer cells or damages …

Cognitive decline has a clear impact on quality of life in patients who have received cranial
radiation treatment. The pathophysiological process is most likely multifactorial, with a …

Purpose There is an annual incidence of 50,000 glioma cases in Europe. The optimal
treatment strategy is highly personalised, depending on tumour type, grade, spatial …