[HTML][HTML] Dissolving microneedles: Applications and growing therapeutic potential

Z Sartawi, C Blackshields, W Faisal - Journal of Controlled Release, 2022 - Elsevier
Microneedles are a rapidly developing method for the transdermal delivery of therapeutic
compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function …

A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

Z Wang, J Luan, A Seth, L Liu, M You, P Gupta… - Nature Biomedical …, 2021 - nature.com
The detection and quantification of protein biomarkers in interstitial fluid is hampered by
challenges in its sampling and analysis. Here we report the use of a microneedle patch for …

Wearable electrochemical sensors for the monitoring and screening of drugs

H Teymourian, M Parrilla, JR Sempionatto… - ACS …, 2020 - ACS Publications
Wearable electrochemical sensors capable of noninvasive monitoring of chemical markers
represent a rapidly emerging digital-health technology. Recent advances toward wearable …

Encoded structural color microneedle patches for multiple screening of wound small molecules

M Lu, X Zhang, D Xu, N Li, Y Zhao - Advanced Materials, 2023 - Wiley Online Library
Detection of biomarkers associated with wound conditions provides in‐depth healthcare
information and benefits wound healing treatment. The current aim of wound detection is to …

Hydrogel‐forming microneedles: current advancements and future trends

JG Turner, LR White, P Estrela… - Macromolecular …, 2021 - Wiley Online Library
In this focused progress review, the recent developments and trends of hydrogel‐forming
microneedles (HFMs) and potential future directions are presented. Previously …

Sampling interstitial fluid from human skin using a microneedle patch

PP Samant, MM Niedzwiecki, N Raviele… - Science translational …, 2020 - science.org
Tissue interstitial fluid (ISF) surrounds cells and is an underutilized source of biomarkers that
complements conventional sources such as blood and urine. However, ISF has received …

Lab under the skin: microneedle based wearable devices

H Teymourian, F Tehrani, K Mahato… - Advanced healthcare …, 2021 - Wiley Online Library
While the current smartwatches and cellphones can readily track mobility and vital signs, a
new generation of wearable devices is rapidly developing to enable users to monitor their …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

Transdermal electroosmotic flow generated by a porous microneedle array patch

S Kusama, K Sato, Y Matsui, N Kimura, H Abe… - Nature …, 2021 - nature.com
A microneedle array is an attractive option for a minimally invasive means to break through
the skin barrier for efficient transdermal drug delivery. Here, we report the applications of …