Adenosine monophosphate-activated protein kinase (AMPK) is a key metabolic sensor that
is pivotal for the maintenance of cellular energy homeostasis. AMPK contributes to diverse …

Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

AMP-activated protein kinase (AMPK) is an important mediator in maintaining cellular
energy homeostasis. AMPK is activated in response to a shortage of energy. Once activated …

Berberine, an important protoberberine isoquinoline alkaloid, has several pharmacological
activities, including antimicrobial, glucose-and cholesterol-lowering, antitumoral, and …

Berberine (BBR), an isoquinoline alkaloid extracted from Coptidis Rhizoma, has a long
history of treating dysentery in the clinic. Over the past two decades, the polytrophic …

Background Inflammation induced by oxidized low-density lipoprotein (ox-LDL) plays an
important role in the pathogenesis of atherosclerosis. Recently, roles of autophagy against …

Berberis vulgaris and berberine, its main component, traditionally have been used for
treatment of various disorders. The pharmacological properties of them have been …

Colorectal cancer is a prevalent malignant tumor with a complex and diverse pathogenesis.
In recent years, natural products have shown promising application prospects as sources of …

Context Berberine (BBR) is used to treat diarrhoea and gastroenteritis in the clinic. It was
found to have anticolon cancer effects. Objective To study the anticolon cancer mechanism …