Sepsis remains a major cause of morbidity and mortality worldwide, with increased burden
in low-and middle-resource settings. The role of the inflammatory response in the …

Systemic inflammation is associated with chronic disease and is purported to be a main
pathogenic mechanism underlying metabolic conditions. Microbes harbored in the host …

Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRR) with a crucial
function in innate immune responses. Activation of TLR4 signaling at the plasma membrane …

Sepsis has affected millions of people worldwide with high mortality rate and lack of effective
strategies. Previous studies have reported that quercetin (Que) can attenuate …

Sepsis is characterized as an uncontrolled host response to infection, and it represents a
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …

Sepsis is a significant public healthcare problem, affecting millions of people worldwide
each year, killing one in four, and increasing in incidence. Thus, advanced therapeutic …

The fever-inducing effect of lipopolysaccharides (LPS) is well known, and human blood is
extremely responsive to this pyrogen. Recently, the safety of LPS-containing food …

Corylin is a main compound isolated from Psoralea corylifolia L.(Fabaceae). A variety of
pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory …

Sepsis is a devastating disease process characterized by a systemic inflammatory response
in the host, evoked by a known or suspected pathogen. Staphylococcus aureus has …

Dysregulated Toll-like receptor (TLR)-4 activation is involved in acute systemic sepsis,
chronic inflammatory diseases, such as atherosclerosis and diabetes, and in viral infections …