Type II diabetes mellitus (T2DM) is a chronic metabolic disease characterized by prolonged
hyperglycemia and insulin resistance (IR). Its incidence is increasing annually, posing a …

Type 2 diabetes mellitus (T2DM) is developed due to the development of insulin resistance
(IR) and pancreatic β cell dysfunction with subsequent hyperglycaemia. Hyperglycaemia …

Diabetic liver injury is a serious complication of type 2 diabetes mellitus (T2DM), which is
often irreversible in the later stage, and affects the quality of life. Autophagy serves an …

A ketogenic diet (KD) is known to have beneficial health effects. Various types of KD
interventions have been applied to manage metabolic syndrome based on modification of …

It has been documented that M2 macrophage polarization plays a suppressive role in
atherosclerosis in diabetes mellitus (DM). In addition, prostaglandin E2 (PGE2) is implicated …

Background Recent clinical and animal studies have shown that renal denervation (RDN)
improves insulin sensitivity and endothelial dysfunction. However, the specific mechanism …

Background Although it is established that caloric restriction offers metabolic and clinical
benefits, the molecular mechanisms underlying these effects remain unclear. Thus, this …

Obesity is characterized by low-grade chronic inflammation, metabolic overload, and
impaired endothelial and cardiovascular function. Roux-en-Y gastric bypass (RYGB) results …

Background: Diabetic liver injury is a serious complication due to the lack of effective
treatments and the unclear pathogenesis. Ferroptosis, a form of cell death involving reactive …

Chronic widespread pain (CWP) is associated with a high rate of disability and decreased
quality of life in people with HIV-1 (PWH). We previously showed that PWH with CWP have …