Isocyanide-based multicomponent reactions in water: Advanced green tools for the synthesis of heterocyclic compounds

T Nasiriani, S Javanbakht, MT Nazeri, H Farhid… - Topics in Current …, 2022 - Springer
Reaction rate acceleration using green methods is an intriguing area of research for
chemists. In this regard, water as a “green solvent” plays a crucial role in the acceleration of …

Non-Canonical Amino Acids as Building Blocks for Peptidomimetics: Structure, Function, and Applications

TG Castro, M Melle-Franco, CEA Sousa… - Biomolecules, 2023 - mdpi.com
This review provides a fresh overview of non-canonical amino acids and their applications in
the design of peptidomimetics. Non-canonical amino acids appear widely distributed in …

Sustainable synthesis of pseudopeptides via isocyanide-Based multicomponent reactions in water

MT Nazeri, T Nasiriani, H Farhid… - ACS Sustainable …, 2022 - ACS Publications
The impressive success in the synthesis of novel products via sustainable and green
methods is a crucial purpose in organic synthesis. Water as a “green solvent” plays a vital …

Multicomponent synthesis and photophysical study of novel α, β-unsaturated carbonyl depsipeptides and peptoids

R González, J Murillo-López, W Rabanal-León… - Frontiers in …, 2023 - frontiersin.org
Multicomponent reactions were performed to develop novel α, β-unsaturated carbonyl
depsipeptides and peptoids incorporating various chromophores such as cinnamic …

Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials

PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2023 - mdpi.com
Cancer is currently considered one of the most threatening diseases worldwide. Diet could
be one of the factors that can be enhanced to comprehensively address a cancer patient's …

Sustainable synthesis of structures containing quinoxaline-pseudopeptide-triazole pharmacophores via a one-pot six-component reaction

H Farhid, HM Araghi, A Shaabani… - New Journal of Chemistry, 2023 - pubs.rsc.org
A sustainable, economical, and straightforward synthetic route based on the higher-order
multicomponent reactions (MCRs) approach for the unification of biologically significant …

Green Pseudo-Seven Component Synthesis of Tris-cyclohexylamino-oxo-benzene-1,3,5-tricarboxylates via Passerini Reaction under Aqueous Conditions

A Azimi-Roshan, H Kiyani… - Current Organic …, 2025 - benthamdirect.com
In this study, a simple, mild, and environmentally friendly process was used for the pseudo-
seven component reaction between readily available benzene-1, 3, 5-tricarboxylic acid …

Consecutive Betti/Bargellini multicomponent reactions: an efficient strategy for the synthesis of naphtho[1,2-f][1,4]oxazepine scaffolds

H Farhid, MT Nazeri, MM Rostami, A Shaabani… - Chemical Papers, 2021 - Springer
An efficient and convenient approach has been developed for the synthesis of naphtho [1, 2-
f][1, 4] oxazepine structures based on the consecutive Betti/Bargellini multicomponent …