The African turquoise killifish: A research organism to study vertebrate aging and diapause

CK Hu, A Brunet - Aging cell, 2018 - Wiley Online Library
The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

MicroRNA biogenesis, gene silencing mechanisms and role in breast, ovarian and prostate cancer

S Khan, H Ayub, T Khan, F Wahid - Biochimie, 2019 - Elsevier
Micro-ribonucleic acids (miRNAs) are important class of short regulatory RNA molecules
involved in regulation of several essential biological processes. In addition to Dicer and …

Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation

E Kelmer Sacramento, JM Kirkpatrick… - Molecular systems …, 2020 - embopress.org
A progressive loss of protein homeostasis is characteristic of aging and a driver of
neurodegeneration. To investigate this process quantitatively, we characterized proteome …

Nothobranchius furzeri, an 'instant' fish from an ephemeral habitat

M Reichard, M Polačik - Elife, 2019 - elifesciences.org
The turquoise killifish, Nothobranchius furzeri, is a promising vertebrate model in ageing
research and an emerging model organism in genomics, regenerative medicine …

Sex chromosome differentiation via changes in the Y chromosome repeat landscape in African annual killifishes Nothobranchius furzeri and N. kadleci

J Štundlová, M Hospodářská, K Lukšíková… - Chromosome …, 2022 - Springer
Homomorphic sex chromosomes and their turnover are common in teleosts. We investigated
the evolution of nascent sex chromosomes in several populations of two sister species of …

[HTML][HTML] Intra-species differences in population size shape life history and genome evolution

D Willemsen, R Cui, M Reichard, DR Valenzano - Elife, 2020 - elifesciences.org
The evolutionary forces shaping life history divergence within species are largely unknown.
Turquoise killifish display differences in lifespan among wild populations, representing an …

[HTML][HTML] Nothobranchius annual killifishes

E Terzibasi Tozzini, A Cellerino - EvoDevo, 2020 - Springer
Annual fishes of the genus Nothobranchius inhabit ephemeral habitats in Eastern and
Southeastern Africa. Their life cycle is characterized by very rapid maturation, a posthatch …

[HTML][HTML] Effects of salinity acclimation on histological characteristics and miRNA expression profiles of scales in juvenile rainbow trout (Oncorhynchus mykiss)

QL Zhou, LY Wang, XL Zhao, YS Yang, Q Ma, G Chen - BMC genomics, 2022 - Springer
Background The scales serve as an ideal model for studying the regulatory mechanism of
bone homeostasis in fish. To explore the effect of salinity acclimation on bone metabolism of …

[HTML][HTML] Genome sequencing and transcriptomic analysis of the Andean killifish Orestias ascotanensis reveals adaptation to high-altitude aquatic life

A Di Genova, G Nardocci, R Maldonado-Agurto… - Genomics, 2022 - Elsevier
Orestias ascotanensis (Cyprinodontidae) is a teleost pupfish endemic to springs feeding into
the Ascotan saltpan in the Chilean Altiplano (3,700 masl) and represents an opportunity to …

[HTML][HTML] Conserved aging-related signatures of senescence and inflammation in different tissues and species

E Barth, A Srivastava, M Stojiljkovic, C Frahm… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Increasing evidence indicates that chronic inflammation and senescence are the cause of
many severe age-related diseases, with both biological processes highly upregulated …