Aging and the male reproductive system

JM Kaufman, B Lapauw, A Mahmoud… - Endocrine …, 2019 - academic.oup.com
This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …

Advanced glycation endproducts in diabetes and diabetic complications

H Vlassara, GE Striker - Endocrinology and Metabolism Clinics, 2013 - endo.theclinics.com
It was initially believed that advanced glycation end products (AGEs) arose primarily from
endogenous sources, and that excess amounts were only present in patients with diabetes …

[HTML][HTML] Estrogens and the regulation of glucose metabolism

M Alemany - World Journal of diabetes, 2021 - ncbi.nlm.nih.gov
The main estrogens: estradiol, estrone, and their acyl-esters have been studied essentially
related to their classical estrogenic and pharmacologic functions. However, their main effect …

Combined effects of sex hormone‐binding globulin and sex hormones on risk of incident type 2 diabetes: 性激素结合球蛋白与性激素联合预测2 型糖尿病的发生

J Hu, A Zhang, S Yang, Y Wang, R Goswami… - Journal of …, 2016 - Wiley Online Library
摘要背景本研究主要目的是探讨性激素结合球蛋白(sex hormone‐binding globulin, SHBG)
与性激素联合作用是否可以预测2 型糖尿病的发生. 方法本研究为一项前瞻性巢式病例对照研究 …

Testosterone level and risk of type 2 diabetes in men: a systematic review and meta-analysis

Q Yao, B Wang, X An, J Zhang… - Endocrine …, 2018 - ec.bioscientifica.com
Background Type 2 diabetes is a risk factor for testosterone deficiency and impaired sex
steroid status. Some studies also investigated the association of testosterone level with …

D-chiro-inositol, an aromatase down-modulator, increases androgens and reduces estrogens in male volunteers: A pilot study

G Monastra, M Vazquez-Levin… - Basic and Clinical …, 2021 - Springer
Background Androgen deficiency affects men in the adulthood, causing several harmful
effects at the reproductive and behavioural levels. Since aromatase is an enzyme that …

Development and validation of LC–MS/MS method for quantification of bisphenol A and estrogens in human plasma and seminal fluid

J Vitku, T Chlupacova, L Sosvorova, R Hampl, M Hill… - Talanta, 2015 - Elsevier
Bisphenol A (BPA) is a widely known endocrine disruptor with estrogenic, antiestrogenic or
antiandrogenic properties. BPA could interfere with estrogen metabolism as well with …

MANAGEMENT OF ENDOCRINE DISEASE: Rationale and current evidence for testosterone therapy in the management of obesity and its complications

B Lapauw, JM Kaufman - European Journal of Endocrinology, 2020 - academic.oup.com
Overt hypogonadism in men adversely affects body composition and metabolic health,
which generally improve upon testosterone (TS) therapy. As obese men often display lower …

Estrogens and body weight regulation in men

KB Rubinow - Sex and Gender Factors Affecting Metabolic …, 2017 - Springer
Our understanding of the metabolic roles of sex steroids in men has evolved substantially
over recent decades. Whereas testosterone once was believed to contribute to metabolic …

The longitudinal relationship of sexual function and androgen status in older men: the Concord Health and Ageing in Men Project

B Hsu, RG Cumming, FM Blyth… - The Journal of …, 2015 - academic.oup.com
Context: It is unclear whether declining sexual function in older men is a cause or
consequence of reduced androgen status. Objective: Longitudinal associations were …