A simple, primary amine bearing a C10H15 alkyl residue was found to display potent anti-
Influenza A properties in 1964. 1 Soon thereafter, antiviral activity of this amine was found …

The recent outbreaks of avian influenza A (H5N1) virus, its expanding geographic
distribution and its ability to transfer to humans and cause severe infection have raised …

The reaction of 5-(1-adamantyl)-1, 3, 4-oxadiazoline-2-thione 2 with iodoethane, 2-
dimethylaminoethyl chloride hydrochloride or 2-piperidinoethyl chloride hydrochloride in …

Reaction of 1-adamantanecarbonyl chloride with certain carboxylic acid hydrazides in
pyridine yielded the corresponding N-acyl adamantane-1-carbohydrazide derivatives 3a–j …

As part of ongoing studies in developing new antimicrobials, a class of structurally novel 4-
thiazolidinone derivatives incorporating three known bioactive nuclei such as thiazole …

Reductive amination is an important tool for synthetic organic chemists in the construction of
carbon‐nitrogen bonds. This reaction, also termed reductive alkylation, involves …

Spirocompounds constitute an important class of organic frameworks enveloping numerous
pharmacological activities, among them, the promising anticancer potential of …

New 1-adamanyl-1, 3, 4-thiadiazole derivatives namely, 5-(1-adamantyl)-1, 3, 4-
thiadiazoline-2-thione 3, 5-(1-adamantyl)-3-(benzyl-or 4-substituted benzyl)-1, 3, 4 …

Synthetic spiro [pyrrolidine-2, 2′-adamantanes] 2, 3, 11, 15, 12, 16, 18, 20 were evaluated
in vitro and found to be active anti-influenza virus A compounds; the effect of the position of …

The synthesis of some new aminoadamantane derivatives is described. The new
compounds were evaluated against a wide range of viruses [influenza A H1N1, influenza A …