Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

Recent advances of controlled drug delivery using microfluidic platforms

ST Sanjay, W Zhou, M Dou, H Tavakoli, L Ma… - Advanced drug delivery …, 2018 - Elsevier
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …

Metabolite-induced in vivo fabrication of substrate-free organic bioelectronics

X Strakosas, H Biesmans, T Abrahamsson, K Hellman… - Science, 2023 - science.org
Interfacing electronics with neural tissue is crucial for understanding complex biological
functions, but conventional bioelectronics consist of rigid electrodes fundamentally …

[HTML][HTML] Wireless optofluidic systems for programmable in vivo pharmacology and optogenetics

JW Jeong, JG McCall, G Shin, Y Zhang, R Al-Hasani… - Cell, 2015 - cell.com
In vivo pharmacology and optogenetics hold tremendous promise for dissection of neural
circuits, cellular signaling, and manipulating neurophysiological systems in awake …

Micropumps and biomedical applications–A review

YN Wang, LM Fu - Microelectronic Engineering, 2018 - Elsevier
This paper presents a review of the current state-of-the-art in micropumping technology for
biomedical applications. The review focuses particularly on the actuation schemes, flow …

A self-powered wireless detachable drug/light injector for metronomic photodynamic therapy in cancer treatment

T Lin, P Zou, R Lin, H Guan, Z Fang, J Chen, Z Long… - Nano Energy, 2023 - Elsevier
Cancer is a growing global health concern, and photodynamic therapy (PDT) has emerged
as a promising technology with minimal side effects for cancer treatment. Miniaturized PDT …

Fully flexible implantable neural probes for electrophysiology recording and controlled neurochemical modulation

MH Malekoshoaraie, B Wu, DD Krahe… - Microsystems & …, 2024 - nature.com
Targeted delivery of neurochemicals and biomolecules for neuromodulation of brain activity
is a powerful technique that, in addition to electrical recording and stimulation, enables a …

Piezoelectric micropumps: State of the art review

H Asadi Dereshgi, H Dal, MZ Yildiz - Microsystem Technologies, 2021 - Springer
The purpose of this paper is to present an overview of problems and some research gaps for
better understanding of piezoelectric micropump studies. Micropumps have important and …

Recent advances in silicon-based neural microelectrodes and microsystems: a review

Z Fekete - Sensors and Actuators B: Chemical, 2015 - Elsevier
Developments in neurotechnology are recently driven by newly national and international
brain research initiatives worldwide. The challenging goal of understanding how the human …

Multimaterial and multifunctional neural interfaces: from surface-type and implantable electrodes to fiber-based devices

C Sung, W Jeon, KS Nam, Y Kim, H Butt… - Journal of Materials …, 2020 - pubs.rsc.org
Neural interfaces have enabled significant advancements in neuroscience and paved the
way for clinical applications in the diagnosis, treatment, and prevention of neurological …