Despite decades of dedicated research, there remains a dire need for new drugs against
tuberculosis (TB). Current therapies are generations old and problematic. Resistance to …

Tuberculosis (TB), one of the most prevalent infections, is on the rise today. Although there
are drugs available in the market to combat this lethal disorder, there are several …

A series of thirty eight novel 3-(4-((substituted-1H-1, 2, 3-triazol-4-yl) methyl) piperazin-1-
yl/1, 4-diazepan-1-yl) benzo [d] isoxazole and 1-(4-(benzo [d] isoxazol-3-yl) piperazin-1-yl/1 …

In the present study, we have designed imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-
b] thiazole derivatives from earlier reported imidazo [1, 2-a] pyridine based Mycobacterium …

Tuberculosis (TB) has become a worldwide threat, mainly due to the emergence of multidrug-
resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis …

Objective (s): This study explored Indonesian Actinobacteria which were isolated from
Curcuma zedoaria endophytic microbes and mangrove ecosystem for new …

Abstract Twenty six 2, 6-disubstituted 4, 5, 6, 7-tetrahydrothieno [2, 3-c] pyridine-3-
carboxamide derivatives were designed by molecular hybridization approach using and …

Abstract Forty 3-phenyl-4, 5, 6, 7-tetrahydro-1H-pyrazolo [4, 3-c] pyridine derivatives were
synthesized from piperidin-4-one by five step synthesis and evaluated for Mycobacterium …

The enzyme pantothenate synthetase, PanC, is an attractive drug target in Mycobacterium
tuberculosis. It is essential for the in vitro growth of M. tuberculosis and for survival of the …

The purpose of this study was to prepare various 1-((1-(substituted)-1H-1, 2, 3-triazol-4-yl)
methyl)-N, 3-diphenyl-6, 7-dihydro-1H-pyrazolo [4, 3-c] pyridine-5 (4H)-carboxamides using …