Human cancer genomes are characterized by widespread aberrations in DNA methylation
patterns including DNA hypomethylation of mostly repetitive sequences and …

Lung cancer is recognized as a leading cause of cancer-related death worldwide and its
frequency is still increasing. The prognosis in lung cancer is poor and limited by the …

Currently, molecular markers are not used when determining the prognosis and treatment
strategy for patients with hepatocellular carcinoma (HCC). In the present study, we proposed …

To clarify the significance of DNA methylation alterations during renal carcinogenesis,
methylome analysis using single-CpG-resolution Infinium array was performed on 29 normal …

Alterations of DNA methylation, which result in chromosomal instability and silencing of
tumor‐related genes, are among the most consistent epigenetic changes observed in …

Liver cancer is the sixth-most-common cancer overall but the third-most-frequent cause of
cancer death. Among primary liver cancers, hepatocellular carcinoma (HCC), the major …

Renal cell carcinoma (RCC) is not a single entity, but comprises a group of tumors including
clear cell RCC, papillary RCC and chromophobe RCC, which arise from the epithelium of …

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infection were known to be risk factors
for HCC, they were suspected to promote its development by eliciting epigenetic changes …

The aim of this study was to clarify the significance of DNA methylation alterations during
non-alcoholic steatohepatitis (NASH)-related hepatocarcinogenesis. Single-CpG-resolution …

Hepatocellular carcinoma (HCC) is the second most common cause of cancer death
worldwide, but is still lacking sensitive and specific biomarkers for early diagnosis and …