Vascular endothelial cells form the inner layer of blood vessels where they have a key role
in the development and maintenance of the functional circulatory system and provide …

In the absence of effective interventions to prevent preterm births, improved survival of
infants who are born at the biological limits of viability has relied on advances in perinatal …

The cell type specific sequences of transcriptional programs during lung regeneration have
remained elusive. Using time-series single cell RNA-seq of the bleomycin lung injury model …

The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

Mesenchymal cells are mesoderm-derived stromal cells that are best known for providing
structural support to organs, synthesizing and remodeling the extracellular matrix (ECM) and …

The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …

During late lung development, alveolar and microvascular development is finalized to
enable sufficient gas exchange. Impaired late lung development manifests as …

Background Recent investigations of the meninges have highlighted the importance of the
dura layer in central nervous system immune surveillance beyond a purely structural role …

Accurate cell type identification is a key and rate-limiting step in single-cell data analysis.
Single-cell references with comprehensive cell types, reproducible and functionally …

Pulmonary endothelial progenitor cells (EPCs) are critical for neonatal lung angiogenesis
and represent a subset of general capillary cells (gCAPs). Molecular mechanisms through …