Cardiovascular disease (CVD) is a serious health challenge, causing more deaths
worldwide than cancer. The vascular endothelium, which forms the inner lining of blood …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

The inflammatory microenvironment involves changes in pH and protein phosphorylation
state and is closely related to the occurrence and development of atherosclerosis (AS) …

Background Lipopolysaccharide, a highly potent endotoxin responsible for severe sepsis, is
the major constituent of the outer membrane of gram-negative bacteria. Endothelial cells …

Ethnopharmacological relevance Atherosclerosis (AS) is a common systemic disease with
increasing morbidity and mortality worldwide. Traditional Chinese medicine (TCM) with …

Atherosclerosis is an inflammatory disease initiated by endothelial activation, in which
lipoprotein, cholesterol, extracellular matrix, and various types of immune and non-immune …

BACKGROUND: In developmental and pathological tissues, nascent vessel networks
generated by angiogenesis require further pruning/regression to delete nonfunctional …

The theory that oxidative damage caused by mitochondrial free radicals leads to aging has
brought mitochondria into the forefront of aging research. Psychological stress that …

Adipokines are biologically active factors secreted by adipose tissue that act on local and
distant tissues through autocrine, paracrine, and endocrine mechanisms. However …

Atherosclerosis (AS) is a chronic vascular disease characterized by lipid accumulation and
the activation of the inflammatory response; it remains the leading nation-wide cause of …