Exercise under heat stress: thermoregulation, hydration, performance implications, and mitigation strategies
JD Périard, TMH Eijsvogels… - Physiological …, 2021 - journals.physiology.org
A rise in body core temperature and loss of body water via sweating are natural
consequences of prolonged exercise in the heat. This review provides a comprehensive and …
consequences of prolonged exercise in the heat. This review provides a comprehensive and …
Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …
mortality worldwide, and its importance is further emphasized in the context of the novel …
Spatially resolved multiomics of human cardiac niches
The function of a cell is defined by its intrinsic characteristics and its niche: the tissue
microenvironment in which it dwells. Here we combine single-cell and spatial …
microenvironment in which it dwells. Here we combine single-cell and spatial …
Renin–angiotensin–aldosterone system inhibitors and risk of Covid-19
HR Reynolds, S Adhikari, C Pulgarin… - … England Journal of …, 2020 - Mass Medical Soc
Background There is concern about the potential of an increased risk related to medications
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …
Renin–angiotensin–aldosterone system blockers and the risk of Covid-19
Background A potential association between the use of angiotensin-receptor blockers
(ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus …
(ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus …
COVID-19, renin-angiotensin system and endothelial dysfunction
R Amraei, N Rahimi - Cells, 2020 - mdpi.com
The newly emergent novel coronavirus disease 2019 (COVID-19) outbreak, which is caused
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …
Inflammation triggered by SARS-CoV-2 and ACE2 augment drives multiple organ failure of severe COVID-19: molecular mechanisms and implications
The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …
A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome
A Khan, C Benthin, B Zeno, TE Albertson, J Boyd… - Critical care, 2017 - Springer
Background Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme
2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome …
2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome …
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Cellular senescence, a stress-induced irreversible growth arrest often characterized by
expression of p16Ink4a (encoded by the Ink4a/Arf locus, also known as Cdkn2a) and a …
expression of p16Ink4a (encoded by the Ink4a/Arf locus, also known as Cdkn2a) and a …
Role of the ACE2/angiotensin 1–7 axis of the renin–angiotensin system in heart failure
Heart failure (HF) remains the most common cause of death and disability, and a major
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …