The human insulin-like growth factor-1 (IGF-1) gene gives rise to multiple, heterogeneous
mRNA transcripts through a combination of multiple transcription initiation sites, alternative …

In the development and maintenance of bone structures resistant to usual mechanical
stresses, adequate nutrition plays an important part. In addition to calcium associated with …

The insulinlike growth factor-I (IGF-I) is an important factor which regulates a variety of
cellular responses in multiple biological systems. The IGF1 gene comprises a highly …

The aim of the present review is to summarise, evaluate and critique the different
mechanisms involved in anabolic growth of skeletal muscle and the catabolic processes …

Transgenic CBA mice expressing either the tyrosine kinase GTK (gut tyrosine kinase) or the
adaptor protein SHB (Src homology 2 protein of beta-cells) under the control of the rat …

Transgenic mice that overexpress insulin-like growth factor-1 (IGF-I) specifically in skeletal
muscle have generated much information about the role of this factor for muscle growth and …

Among osteotrophic nutrients, proteins play an important role in bone development, thereby
influencing peak bone mass. Consequently, protein malnutrition during development can …

Here, we characterise new strains of normal and dystrophic (mdx) mice that overexpress
Class 2 IGF-1 Ea in skeletal myofibres. We show that transgenic mice have increased …

Low-protein diets most often induce increased energy intake in an attempt to increase
protein intake to meet protein needs with a risk of accumulation as fat of the excess energy …

Nutrient supply may control muscle growth directly and indirectly through its influence on
regulatory factors. The present study focuses on its effects on muscle insulin-like growth …