Applications of lysozyme, an innate immune defense factor, as an alternative antibiotic

P Ferraboschi, S Ciceri, P Grisenti - Antibiotics, 2021 - mdpi.com
Lysozyme is a~ 14 kDa protein present in many mucosal secretions (tears, saliva, and
mucus) and tissues of animals and plants, and plays an important role in the innate …

Synergistic photothermal antibacterial therapy enabled by multifunctional nanomaterials: Progress and perspectives

X Bai, Y Yang, W Zheng, Y Huang, F Xu… - Materials Chemistry …, 2023 - pubs.rsc.org
In recent years, infection caused by drug-resistant bacteria has become a serious public
health problem. The exploration of antibacterial therapies other than antibiotics has attracted …

The outer membrane is an essential load-bearing element in Gram-negative bacteria

ER Rojas, G Billings, PD Odermatt, GK Auer, L Zhu… - Nature, 2018 - nature.com
Gram-negative bacteria possess a complex cell envelope that consists of a plasma
membrane, a peptidoglycan cell wall and an outer membrane. The envelope is a selective …

The case for modeling human infection in zebrafish

MC Gomes, S Mostowy - Trends in microbiology, 2020 - cell.com
Zebrafish (Danio rerio) larvae are widely recognized for studying host–pathogen interactions
in vivo because of their optical transparency, genetic manipulability, and translational …

Tree of motility–A proposed history of motility systems in the tree of life

M Miyata, RC Robinson, TQP Uyeda… - Genes to …, 2020 - Wiley Online Library
Motility often plays a decisive role in the survival of species. Five systems of motility have
been studied in depth: those propelled by bacterial flagella, eukaryotic actin polymerization …

L-form conversion in Gram-positive bacteria enables escape from phage infection

JC Wohlfarth, M Feldmüller, A Schneller, S Kilcher… - Nature …, 2023 - nature.com
At the end of a lytic bacteriophage replication cycle in Gram-positive bacteria, peptidoglycan-
degrading endolysins that cause explosive cell lysis of the host can also attack non-infected …

Lysozyme and its modified forms: A critical appraisal of selected properties and potential

G Leśnierowski, T Yang - Trends in Food Science & Technology, 2021 - Elsevier
Background Lysozyme is present in most organisms in the world, in which it performs highly
important protective biological functions. The native form of this enzyme is a monomer that …

Recent insights into the prognostic and therapeutic applications of lysozymes

L Jiang, Y Li, L Wang, J Guo, W Liu, G Meng… - Frontiers in …, 2021 - frontiersin.org
Lysozymes are naturally occurring enzymes present in a variety of biological organisms,
such as bacteria, fungi, and animal bodily secretions and tissues. It is also the main …

Membrane vesicle production as a bacterial defense against stress

N Mozaheb, MP Mingeot-Leclercq - Frontiers in microbiology, 2020 - frontiersin.org
Membrane vesicles are the nano-sized vesicles originating from membranes. The
production of membrane vesicles is a common feature among bacteria. Depending on the …

Possible role of L-form switching in recurrent urinary tract infection

KM Mickiewicz, Y Kawai, L Drage, MC Gomes… - Nature …, 2019 - nature.com
Recurrent urinary tract infection (rUTI) is a major medical problem, especially in the elderly
and infirm, but the nature of the reservoir of organisms responsible for survival and …