RNA-binding proteins (RBPs) are critical effectors of gene expression, and as such their
malfunction underlies the origin of many diseases. RBPs can recognize hundreds of …

N 6-Methyladenosine (m 6 A), the most prevalent internal modification associated with
eukaryotic mRNAs, influences many steps of mRNA metabolism, including splicing, export …

Stress granules and P-bodies are cytosolic biomolecular condensates that dynamically form
by the phase separation of RNAs and proteins. They participate in translational control and …

Noncoding RNA sequences, including long noncoding RNAs, small nucleolar RNAs, and
untranslated mRNA regions, accomplish many of their diverse functions through direct …

RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …

The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

Proximity labeling (PL) with genetically-targeted promiscuous enzymes has emerged as a
powerful tool for unbiased proteome discovery. By combining the spatiotemporal specificity …

Recent efforts towards the comprehensive identification of RNA-bound proteomes have
revealed a large, surprisingly diverse family of candidate RNA-binding proteins (RBPs) …

We have developed CRISPR-assisted RNA–protein interaction detection method (CARPID),
which leverages CRISPR–CasRx-based RNA targeting and proximity labeling to identify …

RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …