Fibrotic diseases, such as systemic sclerosis (SSc), idiopathic pulmonary fibrosis, renal
fibrosis and liver cirrhosis are characterized by tissue overgrowth due to excessive …

Simple Summary Outcomes for patients with acute promyelocytic leukemia (APL) have
improved over the past 40 years due to the development of targeted treatment regimens and …

Fibrosis is an important and essential reparative response to injury that, if left uncontrolled,
results in the excessive synthesis, deposition, remodeling, and stiffening of the extracellular …

Fibrosis is an unavoidable consequence of chronic inflammation. Extracellular matrix
deposition by fibroblasts, stimulated by multiple pathways, is the first step in the onset of …

This review article proposes the theory that liver fibrosis, the abnormal accumulation of
excessive extracellular matrix, is not just an indicator of liver disease but also a negative …

The innate immune system serves as an important biological defense system against
various pathogens within hosts. However, under certain conditions, it can pose a pathogenic …

Idiopathic pulmonary fibrosis (IPF) is associated with a significantly increased risk of
thrombotic events and mortality. This review explores the complex bidirectional relationship …

Background The Cadherin gene family holds immense significance in maintaining the
integrity and functionality of stomach tissues, playing crucial roles in cell-cell adhesion, cell …

Direct oral anticoagulants (DOACs) are the standard treatment for thromboembolic
protection in atrial fibrillation (AF) patients. Epigenetic modifications, such as DNA …

Cardiovascular diseases have become the leading cause of death in urban and rural areas.
Myocardial fibrosis is a common pathological manifestation at the adaptive and repair stage …