Mitochondria are not only important for cellular bioenergetics but also lie at the heart of
critical metabolic pathways. They can rapidly adjust themselves in response to changing …

Pathogen inactivation (PI) for platelet concentrates (PC) is a fairly recent development in
transfusion medicine that is intended to decrease infectious disease transmission from the …

Red blood cell (RBC) concentrates are stored in additive solutions at 4 o C for up to 42 days,
whereas platelets concentrates (PCs) are stored at 22 o C with continuous agitation for up to …

The causative agent of the COVID-19 pandemic, the SARS-CoV-2 virus has yielded multiple
relevant mutations, many of which have branched into major variants. The Omicron variant …

Background: Platelet concentrate (PC) is one of the main products used in a therapeutic
transfusion. This blood component requires special storage at blood banks, however, even …

Aflatoxin B1 (AFB1) is a common crop contaminant, while aflatoxin M1 (AFM1) is implicated
in milk safety. Humans are likely to be simultaneously exposed to AFB1 and AFM1; however …

Background Platelet concentrate (PC) transfusions are crucial in prevention and treatment of
bleeding in infection, surgery, leukemia, and thrombocytopenia patients. Although the …

Platelets are small, anucleate cells that travel as resting discoid fragments in the circulation.
Their average circulating life span is 8–9 days, and their formation is an elegant and finely …

MicroRNAs (miRNAs) are small RNA molecules that modulate gene and protein expression
in hematopoiesis. Platelets are known to contain a fully functional miRNA machinery. While …

Bcl-2 family proteins play key roles in the intrinsic apoptosis pathway in platelets, with both
pro-and antiapoptotic protein expressions regulating survival during ex vivo storage. We …