A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Hydrogen sulphide and its therapeutic potential

C Szabó - Nature reviews Drug discovery, 2007 - nature.com
Hydrogen sulphide (H2S) is increasingly being recognized as an important signalling
molecule in the cardiovascular and nervous systems. The production of H2S from l-cysteine …

Toxicology of hydrogen sulfide.

RJ Reiffenstein, WC Hulbert, SH Roth - Annual review of …, 1992 - europepmc.org
Significant progress has been made in determining the action of sulfide on the primary target
organs. It is reasonably clear that sulfide causes both K (+)-channel-mediated …

Sulfide as an environmental factor and toxicant: tolerance and adaptations in aquatic organisms

T Bagarinao - Aquatic Toxicology, 1992 - Elsevier
This review brings together a large number of independent and seemingly unrelated studies
in various disciplines under four major topics:(1) sulfide as an environmental factor in …

Physiological role of hydrogen sulfide and polysulfide in the central nervous system

H Kimura - Neurochemistry international, 2013 - Elsevier
Hydrogen sulfide (H 2 S) is a well-known toxic gas that has the smell of rotten eggs. This
pungent gas was considered as a physiological mediator, after the identification of …

Hydrogen sulfide is a signaling molecule and a cytoprotectant

H Kimura, N Shibuya, Y Kimura - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Accumulating evidence shows that hydrogen sulfide may function as a
signaling molecule in processes such as neuromodulation in the brain and smooth muscle …

Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol

B Geng, L Chang, C Pan, Y Qi, J Zhao, Y Pang… - Biochemical and …, 2004 - Elsevier
Previous work has shown that the endogenous cystathionine γ-synthase (CSE)/hydrogen
sulfide (H2S) pathway participates in the regulation of cardiac contraction. We hypothesized …

Hydrogen sulfide in the mammalian cardiovascular system

YH Liu, M Lu, LF Hu, PTH Wong… - Antioxidants & redox …, 2012 - liebertpub.com
For more than a century, hydrogen sulfide (H2S) has been regarded as a toxic gas. This
review surveys the growing recognition of the role of H2S as an endogenous signaling …

Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air?

L Li, PK Moore - Trends in pharmacological sciences, 2008 - cell.com
The past two decades have seen an upsurge in interest in the biology of naturally occurring
gases, starting with nitric oxide and extending through to carbon monoxide. The latest …