Design of polymeric carriers for intracellular peptide delivery in oncology applications

S Lv, M Sylvestre, AN Prossnitz, LF Yang… - Chemical …, 2021 - ACS Publications
In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …

Recent advances in nanovaccines using biomimetic immunomodulatory materials

V Vijayan, A Mohapatra, S Uthaman, IK Park - Pharmaceutics, 2019 - mdpi.com
The development of vaccines plays a vital role in the effective control of several fatal
diseases. However, effective prophylactic and therapeutic vaccines have yet to be …

Bioactive nanoparticles for cancer immunotherapy

S Poilil Surendran, MJ Moon, R Park… - International journal of …, 2018 - mdpi.com
Currently, immunotherapy is considered to be one of the effective treatment modalities for
cancer. All the developments and discoveries in this field up to the recent Nobel Prize add to …

In Situ Nanoadjuvant-Assembled Tumor Vaccine for Preventing Long-Term Recurrence

QV Le, J Suh, JJ Choi, GT Park, JW Lee, G Shim… - ACS …, 2019 - ACS Publications
Although immune checkpoint inhibitors have emerged as a breakthrough in cancer therapy,
a monotherapy approach is not sufficient. Here, we report an immune checkpoint inhibitor …

[HTML][HTML] Multifaceted therapeutic applications of biomimetic nanovaccines

D Chheda, S Shete, T Tanisha, SD Bahadure… - Drug Discovery …, 2024 - Elsevier
The development of vaccines has had a crucial role in preventing and controlling infectious
diseases on a global scale. Innovative formulations of biomimetic vaccines inspired by …

Nanovaccines for cancer immunotherapy: Focusing on complex formation between adjuvant and antigen

NH Goradel, M Nemati, A Bakhshandeh… - International …, 2023 - Elsevier
As an interesting cancer immunotherapy approach, cancer vaccines have been developed
to deliver tumor antigens and adjuvants to antigen-presenting cells (APCs). Although the …

Gold nanostructures in melanoma: advances in treatment, diagnosis, and theranostic applications

ZS Dastgheib, SS Abolmaali, G Farahavar… - Heliyon, 2024 - cell.com
Melanoma, a lethal form of skin cancer, poses a significant challenge in oncology due to its
aggressive nature and high mortality rates. Gold nanostructures, including gold …

Advanced nanovaccines based on engineering nanomaterials for accurately enhanced cancer immunotherapy

D Wang, W Gu, W Chen, J Zhou, L Yu, BK Kim… - Coordination Chemistry …, 2022 - Elsevier
In recent years, nanovaccine based on nanomaterials emerging as an advanced
nanotechnology has drawn more attention for accurately enhancing anti-tumor …

A sugar modified amphiphilic cationic nano-adjuvant ceased tumor immune suppression and rejuvenated peptide vaccine induced antitumor immunity in cervical …

A Mohapatra, SK Rajendrakumar, K Cherukula… - Biomaterials …, 2023 - pubs.rsc.org
Human papilloma virus (HPV), one of the most common cancer-causing viruses, accounts
for more than 90% of human anal and cervical cancers. Clinical studies have focused on …

Enhancing cancer immunotherapy with mannose mimicking glycopolymer nanoparticles induced activation of dendritic cells

K Bhamidipati, NMR Nakka, M Ahmed, K Javvaji… - Bioorganic …, 2024 - Elsevier
Cancer immunotherapy leverages the immune system's inherent capacity to combat
malignancies. However, effective stimulation of Dendritic cells (DCs) is challenging due to …