Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

JV Higdon, B Delage, DE Williams… - Pharmacological …, 2007 - Elsevier
Cruciferous vegetables are a rich source of glucosinolates and their hydrolysis products,
including indoles and isothiocyanates, and high intake of cruciferous vegetables has been …

Taste and flavor perceptions of glucosinolates, isothiocyanates, and related compounds

L Bell, OO Oloyede, S Lignou… - Molecular Nutrition & …, 2018 - Wiley Online Library
Brassicaceae plants are renowned for their taste, aroma and trigeminal characteristics;
predominantly bitter taste, sulfurous aroma, and pungency. Compounds responsible for …

Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin.

LF Bjeldanes, JY Kim, KR Grose… - Proceedings of the …, 1991 - National Acad Sciences
Indole-3-carbinol (I3C) is a secondary plant metabolite produced in vegetables of the
Brassica genus, including cabbage, cauliflower, and brussels sprouts. I3C is both an anti …

A review of mechanisms underlying anticarcinogenicity by brassica vegetables

DTH Verhoeven, H Verhagen, RA Goldbohm… - Chemico-biological …, 1997 - Elsevier
The mechanisms by which brassica vegetables might decrease the risk of cancer are
reviewed in this paper. Brassicas, including all types of cabbages, broccoli, cauliflower and …

Molecular targets and anticancer potential of indole-3-carbinol and its derivatives

BB Aggarwal, H Ichikawa - Cell cycle, 2005 - Taylor & Francis
Indole-3-carbinol (I3C) is produced by members of the family Cruciferae, and particularly
members of the genus Brassica (eg, cabbage, radishes, cauliflower, broccoli, Brussels …

Bioactive organosulfur phytochemicals in Brassica oleracea vegetables—a review

GS Stoewsand - Food and chemical toxicology, 1995 - Elsevier
Sulfur-containing phytochemicals of two different kinds are present in all Brassica oleracea
(Cruciferae) vegetables (cabbage, broccoli, etc.). They are glucosinolates (previously called …

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

HAJ Schut, EG Snyderwine - Carcinogenesis, 1999 - academic.oup.com
The heterocyclic amines (HCAs) are a family of mutagenic/carcinogenic compounds
produced during the pyrolysis of creatine, amino acids and proteins. The major subclass of …

Antimutagens as cancer chemopreventive agents in the diet

LR Ferguson - … Research/Fundamental and Molecular Mechanisms of …, 1994 - Elsevier
It has been suggested that the use of antimutagens and anticarcinogens in everyday life will
be the most effective procedure for preventing human cancer and genetic disease. There …

Bcl-2 family-mediated apoptotic effects of 3, 3′-diindolylmethane (DIM) in human breast cancer cells

C Hong, GL Firestone, LF Bjeldanes - Biochemical pharmacology, 2002 - Elsevier
3, 3′-Diindolylmethane (DIM) is a major invivo derivative of the putative anticancer agent
indole-3-carbinol (I3C), which is present in vegetables of the Brassica genus. At …

Cruciferous vegetables and cancer prevention

G Murillo, RG Mehta - Nutrition and cancer, 2001 - Taylor & Francis
In recent years, cancer prevention by natural products has received considerable attention.
The potential protective role of cruciferous vegetables and active components present in …