Cell senescence (CS) is at the nexus between aging and associated chronic disorders, and
aging increases the burden of CS in all major metabolic tissues. However, CS is also …

With the aging of global population, the incidence of nonalcoholic fatty liver disease
(NAFLD) has surged in recent decades. NAFLD is a multifactorial disease that follows a …

Senescent cell accumulation has been observed in age-associated diseases including
cardiovascular diseases. Senescent cells lack proliferative capacity and secrete senescence …

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as non-
alcoholic fatty liver disease) is a leading cause of chronic liver disease worldwide. MASLD …

Cellular senescence is accelerated by hyperglycemia through multiple pathways. Therefore,
senescence is an important cellular mechanism to consider in the pathophysiology of type 2 …

Aims As our comprehension of the intricate relationship between cellular senescence and
tumor biology continues to evolve, the therapeutic potential of cellular senescence is gaining …

Mitochondrial polarity is a critical indicator of numerous pathological and biological
processes; thus, the development of fluorescent probes capable of targeting mitochondria …

Advancements in omics technologies and artificial intelligence (AI) methodologies are
fuelling our progress towards personalised diagnosis, prognosis and treatment strategies in …

Hepatocellular carcinoma (HCC) has become the fourth leading cause of cancer-related
deaths worldwide; annually, approximately 830,000 deaths related to liver cancer are …

Senescence is an important cellular program occurring in development, tissue repair,
cancer, and aging. Increased senescence is also associated with disease states, including …