Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Bibliometric and visualized analysis of ocular drug delivery from 2001 to 2020

C Peng, L Kuang, J Zhao, AE Ross, Z Wang… - Journal of Controlled …, 2022 - Elsevier
Objective To perform a bibliometric analysis in the field of ocular drug delivery research to
characterize the current international trends and to present visual representations of the past …

[HTML][HTML] Block copolymer micelles as ocular drug delivery systems

AA Assiri, K Glover, D Mishra, D Waite, LK Vora… - Drug discovery today, 2024 - Elsevier
Highlights•Amphiphilic polymers self-assemble into block copolymer micelles in
solution.•Polymeric micelles have longer and better contact with the ocular …

[HTML][HTML] MiRNA 24-3p-rich exosomes functionalized DEGMA-modified hyaluronic acid hydrogels for corneal epithelial healing

X Sun, W Song, L Teng, Y Huang, J Liu, Y Peng, X Lu… - Bioactive Materials, 2023 - Elsevier
The damage of corneal epithelium may lead to the formation of irreversible corneal opacities
and even blindness. The migration rate of corneal epithelial cells directly affects corneal …

Gout therapeutics and drug delivery

X Peng, X Li, B Xie, Y Lai, A Sosnik, H Boucetta… - Journal of Controlled …, 2023 - Elsevier
Gout is a common inflammatory arthritis caused by persistently elevated uric acid levels.
With the improvement of people's living standards, the consumption of processed food and …

Ocular drug delivery: advancements and innovations

B Tian, E Bilsbury, S Doherty, S Teebagy, E Wood… - Pharmaceutics, 2022 - mdpi.com
Ocular drug delivery has been significantly advanced for not only pharmaceutical
compounds, such as steroids, nonsteroidal anti-inflammatory drugs, immune modulators …

Formulation and characterization of epalrestat-loaded polysorbate 60 cationic niosomes for ocular delivery

A Kattar, A Quelle-Regaldie, L Sánchez, A Concheiro… - Pharmaceutics, 2023 - mdpi.com
The aim of this work was to develop niosomes for the ocular delivery of epalrestat, a drug
that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol …

Hyaluronic acid-based nanoparticles to deliver drugs to the ocular posterior segment

H Jiang, Z Xu - Drug Delivery, 2023 - Taylor & Francis
Ocular posterior segment diseases such as uveitis, X-linked juvenile retinoschisis, or age-
related macular degeneration usually result in progressive and irreversible vision loss …

Targeting colorectal cancer cells with niosomes systems loaded with two anticancer drugs models; comparative in vitro and anticancer studies

SW El-Far, HA Abo El-Enin, EM Abdou, OE Nafea… - Pharmaceuticals, 2022 - mdpi.com
Colorectal cancer (CRC) is considered one of the most commonly diagnosed malignant
diseases. Recently, there has been an increased focus on using nanotechnology to resolve …