Circadian rhythms are∼ 24-h oscillations in behavior and physiology, which are internally
generated and function to anticipate the environmental changes associated with the solar …

The last few years have witnessed a rapid increase in our knowledge of the retinoid-related
orphan receptors RORα,-β, and-γ (NR1F1-3), their mechanism of action, physiological …

Vitamin D deficiency is implicated in autoimmune disease. We therefore evaluated the
effects of 1α, 25-dihydroxyvitamin D 3 (1, 25-D 3), the active form of vitamin D, on the …

The retinoic acid-related orphan receptor α (RORα) is an orphan member of the subfamily 1
of nuclear hormone receptors. No X-ray structure of RORα has been described so far, and …

The present invention relates to a first group of novel genes, here identified as “genomic
address messenger” or “GAM” genes, and a second group of novel operon-like genes, here …

The nuclear receptor superfamily, a group of structurally related, ligand-dependent
transcription factors, includes a large number of orphan receptors for which no ligand has …

The nuclear hormone receptor retinoic acid‐related orphan receptor (ROR) γt is required for
the development of lymph nodes (LNs) and Peyer's patches (PPs), as these organs are …

The circadian clock is an endogenous time keeping system that controls the physiology and
behavior of many organisms. The transcription factor Brain and Muscle ARNT-like Protein 1 …

The retinoic acid receptor-related receptors (RORs) are members of the nuclear receptor
(NR) superfamily of transcription factors. Several NRs are still characterized as orphan …

The circadian timing system is a complex biological network of interacting circadian clocks
that regulates 24 h rhythms of behavioral and physiological processes. One intriguing …