[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Abstract The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA)
Consortium is a collaborative network of researchers working together on a range of large …
Consortium is a collaborative network of researchers working together on a range of large …
[HTML][HTML] The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies
AT Amare, KO Schubert, M Klingler-Hoffmann… - Translational …, 2017 - nature.com
Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene
studies have identified genetic variants associated with cardiovascular diseases, metabolic …
studies have identified genetic variants associated with cardiovascular diseases, metabolic …
Cross-ancestry genome-wide association meta-analyses of hippocampal and subfield volumes
N Liu, L Zhang, T Tian, J Cheng, B Zhang, S Qiu… - Nature Genetics, 2023 - nature.com
The hippocampus is critical for memory and cognition and neuropsychiatric disorders, and
its subfields differ in architecture and function. Genome-wide association studies on …
its subfields differ in architecture and function. Genome-wide association studies on …
Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics
M Alda - Molecular psychiatry, 2015 - nature.com
After decades of research, the mechanism of action of lithium in preventing recurrences of
bipolar disorder remains only partially understood. Lithium research is complicated by the …
bipolar disorder remains only partially understood. Lithium research is complicated by the …
Molecular genetic studies of ADHD and its candidate genes: a review
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset psychiatric
disorder with high heritability. In recent years, numerous molecular genetic studies have …
disorder with high heritability. In recent years, numerous molecular genetic studies have …
Phenotypes, mechanisms and therapeutics: insights from bipolar disorder GWAS findings
Genome-wide association studies (GWAS) have reported substantial genomic loci
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …
Genetic overlap between attention-deficit/hyperactivity disorder and bipolar disorder: evidence from genome-wide association study meta-analysis
Background Attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BPD) are
frequently co-occurring and highly heritable mental health conditions. We hypothesized that …
frequently co-occurring and highly heritable mental health conditions. We hypothesized that …
The genome-wide risk alleles for psychiatric disorders at 3p21. 1 show convergent effects on mRNA expression, cognitive function, and mushroom dendritic spine
Z Yang, D Zhou, H Li, X Cai, W Liu, L Wang… - Molecular …, 2020 - nature.com
Schizophrenia and bipolar disorder (BPD) are believed to share clinical features, etiological
factors, and disease pathologies (such as impaired cognitive functions and dendritic spine …
factors, and disease pathologies (such as impaired cognitive functions and dendritic spine …
Neurodevelopmental origins of bipolar disorder: iPSC models
KS O'Shea, MG McInnis - Molecular and Cellular Neuroscience, 2016 - Elsevier
Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …
fluctuations in mood from mania to depression. Adoption, twin and family studies have …
Translational genomics and beyond in bipolar disorder
Genome-wide association studies (GWAS) have revealed multiple genomic loci conferring
risk of bipolar disorder (BD), providing hints for its underlying pathobiology. However, there …
risk of bipolar disorder (BD), providing hints for its underlying pathobiology. However, there …