Intestinal barrier in human health and disease

N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

The influence of neuroinflammation in Autism Spectrum Disorder

SM Matta, EL Hill-Yardin, PJ Crack - Brain, behavior, and immunity, 2019 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

GZ Réus, GR Fries, L Stertz, M Badawy, IC Passos… - Neuroscience, 2015 - Elsevier
Psychiatric disorders, including major depressive disorder (MDD), bipolar disorder (BD) and
schizophrenia, affect a significant percentage of the world population. These disorders are …

Inflammation and neuro-immune dysregulations in autism spectrum disorders

D Siniscalco, S Schultz, AL Brigida, N Antonucci - Pharmaceuticals, 2018 - mdpi.com
Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social
communication and interaction and restricted-repetitive patterns of behavior, interests, or …

The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

A systematic review of the valproic-acid-induced rodent model of autism

D Chaliha, M Albrecht, M Vaccarezza… - Developmental …, 2020 - karger.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …

Neuron-glia interactions in neurodevelopmental disorders

YS Kim, J Choi, BE Yoon - Cells, 2020 - mdpi.com
Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

Three decades of valproate: a current model for studying autism Spectrum disorder

D Zarate-Lopez, AL Torres-Chávez… - Current …, 2024 - benthamdirect.com
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …

The impact of neuroimmune alterations in autism spectrum disorder

C Gottfried, V Bambini-Junior, F Francis… - Frontiers in …, 2015 - frontiersin.org
Autism spectrum disorder (ASD) involves a complex interplay of both genetic and
environmental risk factors, with immune alterations and synaptic connection deficiency in …