Multiple sclerosis (MS) is a chronic disease with an inflammatory and neurodegenerative
pathology. Axonal loss and neurodegeneration occurs early in the disease course and may …

Multiple sclerosis (MS) is a chronic, progressive disease of the central nervous system that is
characterised by inflammatory damage to the myelin sheath. Though often neglected …

Objective To assess whether it is feasible to establish specific cut-off values able to
discriminate 'physiological'or 'pathological'brain volume rates in patients with multiple …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system
characterized by focal or diffuse inflammation, demyelination, axonal loss and …

Multiple sclerosis (MS) is an autoimmune, chronic, progressive disease leading to a
combination of inflammation, demyelination, and neurodegeneration throughout the central …

Brain morphometry is usually based on non‐enhanced (pre‐contrast) T1‐weighted MRI.
However, such dedicated protocols are sometimes missing in clinical examinations. Instead …

Background Heterogeneous processes may contribute to cognitive impairment in multiple
sclerosis (MS). Objective To apply a longitudinal multiparametric MRI approach to identify …

Introduction As neurodegeneration is recognized as a major contributor to disability in
multiple sclerosis (MS), brain atrophy quantification could have a high added value in …

Objectives How practice effect influences cognitive testing measured by monthly Symbol
Digit Modalities Test (SDMT) during natalizumab treatment, and what factors confound such …

Of the more than two million people worldwide with multiple sclerosis, 40% to 65%
experience cognitive impairment, many of them early in the course of the disease. Cognitive …