Structural and catalytic properties of histidyl-tRNA synthetase: A potential drug target against leishmaniasis
Visceral leishmaniasis is caused by Leishmania donovani which affects the poorer sections
of society, and despite the global spread, effective treatment is unavailable. The current …
of society, and despite the global spread, effective treatment is unavailable. The current …
Unraveling the peculiarities and development of novel inhibitors of leishmanial arginyl‐tRNA synthetase
F Nasim, MS Kumar, M Alvala, IA Qureshi - The FEBS Journal, 2024 - Wiley Online Library
Aminoacylation by tRNA synthetase is a crucial part of protein synthesis and is widely
recognized as a therapeutic target for drug development. Unlike the arginyl‐tRNA …
recognized as a therapeutic target for drug development. Unlike the arginyl‐tRNA …
Fragment-based QSAR study to explore the structural requirements of DPP-4 inhibitors: a stepping stone towards better type 2 diabetes mellitus management
ABSTRACT Dipeptidyl peptidase-4 (DPP-4) inhibitors belong to a prominent group of
pharmaceutical agents that are used in the governance of type 2 diabetes mellitus (T2DM) …
pharmaceutical agents that are used in the governance of type 2 diabetes mellitus (T2DM) …
[HTML][HTML] Isopentyl caffeate as a promising drug for the treatment of leishmaniasis: An in silico and in vivo study
WS Mota, SSC Oliveira, MM Pereira, DP Souza… - Current Research in …, 2024 - Elsevier
Leishmaniasis is recognised as the second largest parasitic disease worldwide and yet a
neglected disease. The current pharmacological treatments are associated with significant …
neglected disease. The current pharmacological treatments are associated with significant …
Crystal structure of glutamyl-tRNA synthetase from Helicobacter pylori
DE Davis, JP Ayanlade, DT Laseinde… - Structural Biology and …, 2024 - journals.iucr.org
Helicobacter pylori is one of the most common bacterial infections; over two-thirds of the
world's population is infected by early childhood. Persistent H. pylori infection results in …
world's population is infected by early childhood. Persistent H. pylori infection results in …
[PDF][PDF] Current Research in Biotechnology
AK Rout, PS Tripathy, S Dixit, DU Behera… - Current Research in …, 2024 - researchgate.net
ABSTRACT The river Ganges in India has faced considerable issues due to water quality
degradation caused by various anthropogenic activities. This study employs metagenomic …
degradation caused by various anthropogenic activities. This study employs metagenomic …