This review is focused on purinergic neurotransmission, ie, ATP released from nerves as a
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …

This paper, written for the symposium in honour of more than 40 years' contribution to
autonomic research by Professor Geoffrey Burnstock, highlights the progress made in …

Covers all aspects of the structure, function, neurochemistry, transmitter identification and
development of the enteric nervous system This book brings together extensive knowledge …

In 1929 Drury and Szent-Györgyi published a seminal paper describing the potent actions of
adenine compounds. Some decades later, adenosine 5'-triphosphate (ATP) was proposed …

Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance
released by non-adrenergic inhibitory Page 1 Br. J. Pharmac. (1970), 40, 668-688. Evidence …

Purinergic signalling is now recognized to be involved in a wide range of activities of the
nervous system, including neuroprotection, central control of autonomic functions, neural …

New Findings• What is the topic of this review? This is a personal historical review about the
discovery and the main conceptual advances leading to our current understanding of …

Purinergic signaling was proposed in 1972, after it was demonstrated that adenosine 5′-
triphosphate (ATP) was a transmitter in nonadrenergic, noncholinergic inhibitory nerves …

While there were early papers about the extracellular actions of purines, the role of ATP as a
purinergic neurotransmitter in nonadrenergic, noncholinergic nerves in the gut and bladder …

Abstract Professor Geoffrey Burnstock proposed the concept of purinergic signaling via P1
and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …