The in vivo biofilm

T Bjarnsholt, M Alhede, M Alhede… - Trends in …, 2013 - cell.com
Bacteria can grow and proliferate either as single, independent cells or organized in
aggregates commonly referred to as biofilms. When bacteria succeed in forming a biofilm …

The limitations of in vitro experimentation in understanding biofilms and chronic infection

AEL Roberts, KN Kragh, T Bjarnsholt… - Journal of Molecular …, 2015 - Elsevier
We have become increasingly aware that, during infection, pathogenic bacteria often grow
in multicellular biofilms that are often highly resistant to antibacterial strategies. In order to …

[HTML][HTML] ESCMID guideline for the diagnosis and treatment of biofilm infections 2014

N Høiby, T Bjarnsholt, C Moser, GL Bassi… - Clinical microbiology …, 2015 - Elsevier
Biofilms cause chronic infections in tissues or by developing on the surfaces of medical
devices. Biofilm infections persist despite both antibiotic therapy and the innate and adaptive …

The role of bacterial biofilms in chronic infections

T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Biofilms in infections of the eye

PJM Bispo, W Haas, MS Gilmore - Pathogens, 2015 - mdpi.com
The ability to form biofilms in a variety of environments is a common trait of bacteria, and
may represent one of the earliest defenses against predation. Biofilms are multicellular …

The consequences of being in an infectious biofilm: microenvironmental conditions governing antibiotic tolerance

M Sønderholm, T Bjarnsholt, M Alhede… - International journal of …, 2017 - mdpi.com
The main driver behind biofilm research is the desire to understand the mechanisms
governing the antibiotic tolerance of biofilm-growing bacteria found in chronic bacterial …

Clinical and microbiological aspects of biofilm-associated surgical site infections

CE Edmiston Jr, AJ McBain, C Roberts… - Biofilm-based Healthcare …, 2014 - Springer
While microbial biofilms have been recognized as being ubiquitous in nature for the past 40
years, it has only been within the past 20 years that clinical practitioners have realized that …

Proximal lacrimal obstructions: a review

MG Fiorino, C Quaranta‐Leoni… - Acta …, 2021 - Wiley Online Library
Purpose The aims of the review are to summarize the aethiopathogenesis, management
and outcomes of different treatments of proximal lacrimal obstructions. Methods An …

Conjunctivodacryocystorhinostomy with Jones tube: a history and update

EA Steele - Current opinion in ophthalmology, 2016 - journals.lww.com
Conjunctivodacryocystorhinostomy (CDCR) with placement of a Jones tube remains the
gold standard for management of upper lacrimal obstruction. This article provides an …

Microbiologic trends and biofilm growth on explanted periorbital biomaterials: a 30-year review

DB Samimi, BP Bielory, D Miller… - Ophthalmic Plastic & …, 2013 - journals.lww.com
Purpose: To investigate microbiologic trends and role of biofilm on periorbital biomaterials
surgically explanted for recalcitrant infection. Methods: A search of the Bascom Palmer Eye …