2018 update on intravitreal injections: euretina expert consensus recommendations

A Grzybowski, R Told, S Sacu, F Bandello… - …, 2018 - karger.com
Intravitreal injections (IVI) have become the most common intraocular procedure worldwide
with increasing numbers every year. The article presents the most up-to-date review on IVI …

Extraocular, periocular, and intraocular routes for sustained drug delivery for glaucoma

UB Kompella, RR Hartman, MA Patil - Progress in retinal and eye research, 2021 - Elsevier
Although once daily anti-glaucoma drug therapy is a current clinical reality, most therapies
require multiple dosing and there is an unmet need to develop convenient, safe, and …

Intravitreal injection technique and monitoring: updated guidelines of an expert panel

RL Avery, SJ Bakri, MS Blumenkranz, AJ Brucker… - Retina, 2014 - journals.lww.com
Purpose: To review evidence and provide updated guidelines on intravitreal (IVT) injection
technique and monitoring. Methods: A review of the published literature on IVT injection from …

Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections

GB Melo, NFS da Cruz, GG Emerson… - Progress in Retinal and …, 2021 - Elsevier
Intravitreal injections have become the most commonly performed intraocular treatments
worldwide. Because intravitreal injections may induce severe adverse events, such as …

Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress

Y Shen, J Sun, X Sun - Journal of Nanobiotechnology, 2023 - Springer
Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …

Endophthalmitis following intravitreal anti-vascular endothelial growth factor (VEGF) injection: a comprehensive review

R Merani, AP Hunyor - International journal of retina and vitreous, 2015 - Springer
The purpose of this review is to report and summarize previously reported studies and
assess many of the individual steps of the intravitreal injection procedure's possible effect on …

Intravitreal, subretinal, and suprachoroidal injections: evolution of microneedles for drug delivery

RR Hartman, UB Kompella - Journal of Ocular Pharmacology and …, 2018 - liebertpub.com
Even though the very thought of an injection into the eye may be frightening, an estimated 6
million intravitreal (IVT) injections were made in the USA during 2016. With the introduction …

Validation of hyaluronic acid-agar-based hydrogels as vitreous humor mimetics for in vitro drug and particle migration evaluations

SS Thakur, SK Shenoy, JS Suk, JS Hanes… - European Journal of …, 2020 - Elsevier
Artificial vitreous humor holds immense potential for use in in vitro intravitreal drug delivery
assays. In this study, we investigated rheological properties and drug or nanoparticle …

FACTORS AFFECTING PATIENTS'PAIN INTENSITY DURING IN OFFICE INTRAVITREAL INJECTION PROCEDURE

L Rifkin, S Schaal - Retina, 2012 - journals.lww.com
Purpose: To determine factors associated with patients' comfort during routine in-office
intravitreal injection. Methods: Sixty patients receiving intravitreal injections over 15 months …

Preclinical challenges for developing long acting intravitreal medicines

S Awwad, C Henein, N Ibeanu, PT Khaw… - European Journal of …, 2020 - Elsevier
The majority of blinding conditions arise due to chronic pathologies in the retina. During the
last two decades, antibody-based medicines administered by intravitreal injection directly …