Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Association between ambient particulate matter exposure and metabolic syndrome risk: a systematic review and meta-analysis

J Ning, Y Zhang, H Hu, W Hu, L Li, Y Pang, S Ma… - Science of the total …, 2021 - Elsevier
Although the association between ambient particulate matter and metabolic syndrome
(MetS) has been investigated, the effect of particulate matter (PM) on MetS is inconclusive …

2, 5-Dihydroxyterephthalic Acid: A Matrix for Improved Detection and Imaging of Amino Acids

J Fu, J Gu, Z Bao, Y Zhou, H Hu, C Yang… - Analytical …, 2023 - ACS Publications
Amino acids (AAs), which are low-molecular-weight (low-MW) metabolites, serve as
essential building blocks not only for protein synthesis but also for maintaining the nitrogen …

It is time for a moonshot to find “Cures” for diabetic retinal disease

SR Levine, P Sapieha, S Dutta, JK Sun… - Progress in Retinal and …, 2022 - Elsevier
Diabetic retinal disease (DRD), the most common complication of diabetes and a leading
cause of blindness in working age individuals, is now understood to be a form of sensory …

Mitochondria-associated endoplasmic reticulum membrane (MAM): a dark horse for diabetic cardiomyopathy treatment

Y Liu, JL Huo, K Ren, S Pan, H Liu, Y Zheng… - Cell Death …, 2024 - nature.com
Diabetic cardiomyopathy (DCM), an important complication of diabetes mellitus (DM), is one
of the most serious chronic heart diseases and has become a major cause of heart failure …

[HTML][HTML] Targeted metabolomics reveals the aberrant energy status in diabetic peripheral neuropathy and the neuroprotective mechanism of traditional Chinese …

B Zhao, Q Zhang, Y He, W Cao, W Song… - Journal of Pharmaceutical …, 2024 - Elsevier
Diabetic peripheral neuropathy (DPN) is a common and devastating complication of
diabetes, for which effective therapies are currently lacking. Disturbed energy status plays a …

Amino acid analysis as a method of discovering biomarkers for diagnosis of diabetes and its complications

D Cai, B Hou, SL Xie - Amino Acids, 2023 - Springer
Diabetes mellitus (DM) is a severe chronic diseases with a global prevalence of 9%, leading
to poor health and high health care costs, and is a direct cause of millions of deaths each …

Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes

D Ziegler, A Strom, K Straßburger, B Knebel, GJ Bönhof… - Diabetologia, 2021 - Springer
Aims/hypothesis Emerging evidence suggests that in addition to hyperglycaemia,
dyslipidaemia could represent a contributing pathogenetic factor to diabetic neuropathy …

[HTML][HTML] Role of succinate in airway epithelial cell regulation following traumatic lung injury

MV Suresh, S Aktay, G Yalamanchili, S Solanki… - JCI insight, 2023 - ncbi.nlm.nih.gov
Lung contusion and gastric aspiration (LC and GA) are major risk factors for developing
acute respiratory distress following trauma. Hypoxia from lung injury is mainly regulated by …

Salbutamol ameliorates skeletal muscle wasting and inflammatory markers in streptozotocin (STZ)-induced diabetic rats

A Kumar, P Prajapati, V Raj, SC Kim, V Mishra… - International …, 2023 - Elsevier
Diabetes accelerates muscle atrophy, leading to the deterioration of skeletal muscles. This
study aimed to assess the potential of the β2-adrenoceptor agonist, salbutamol (SLB), to …