Primordial germ cells (PGCs) are precursor cells of sperm and eggs. The fate decisions of
chicken PGCs in terms of their development, integrity, and sex determination have unique …

Generating biopharmaceuticals in genetically engineered bioreactors continues to reign
supreme. Hence, genetically engineered birds have attracted considerable attention from …

Avian germ cells can be distinguished by certain characteristics during development. On the
basis of these characteristics, germ cells can be used for germline transmission. However …

The cultivation and expansion of chicken primordial germ cells (cPGCs) are of critical
importance for both biotechnological applications and the management of poultry genetic …

Simple Summary Mesenchymal stem cells (MSCs) are multipotent stem cells that are
capable of differentiation into bone, muscle, fat, and closely related lineages and express …

When derived from chicken embryos, avian primordial germ cells (PGCs) have been
reported to keep their germline-specific properties and proliferative potential even after long …

Primordial germ cells (PGCs) are precursors of functional gametes and can be used as
efficient transgenic tools and carriers in bioreactors. Few methods for long-term culture of …

Abstract Background Genes, RNAs, and proteins play important roles during germline
development. However, the functions of non-coding RNAs (ncRNAs) on germline …

Although chicken spermatogonial stem cells (SSCs) have received considerable attention in
recent years, only a few studies so far have focused on their derivation and characterization …

This study investigates the role of histone acetylation in the differentiation of chicken
embryonic stem cells (ESCs) into primordial germ cells (PGCs). Transcriptomic sequencing …