Objective: To review extant literature implicating inflammation in the pathophysiology of
bipolar disorder. Furthermore, we review evidence regarding the anti-inflammatory actions …

Growing evidence suggests that the immune, endocrine, and nervous systems interact with
each other through cytokines, hormones, and neurotransmitters. The activation of the …

Abstract Rationale Atypical antipsychotic drugs (AAPDs) such as olanzapine have a serious
side effect profile including weight gain and metabolic dysfunction, and a number of studies …

Many pregnancies are lost during early gestation, but clinicians still lack tools to recognize
risk factors for miscarriage. Thus, the identification of risk factors for miscarriage during the …

Objective: Whilst dopaminergic dysfunction remains a necessary component involved in the
pathogenesis of schizophrenia, our current pharmacological armoury of dopamine …

Despite their high degree of effectiveness in the management of psychiatric conditions,
exposure to antipsychotic drugs, including olanzapine and risperidone, is frequently …

Objective: To characterize a model of atypical antipsychotic drug‐induced obesity and
evaluate its mechanism. Research Methods and Procedures: Chronically, olanzapine or …

Clozapine is an effective antipsychotic medication used for treatment‐resistant
schizophrenia. However, it is underutilized due to rigorous hematologic monitoring …

BACKGROUND: Many adverse effects of atypical antipsychotic treatment are associated
with antagonism of monoamine receptors; however, data indicate that important metabolic …

BACKGROUND: Excessive body weight gain (BWG) is a clinically relevant side effect of
olanzapine administration. The primary objective of this study was to assess whether …